Helicobacter Pylori Eradication in Patients with Chronic Renal Failure.
Background and Objectives: Gastrointestinal (GI) complains are common in hemodialysis patients. More than 80% of patients undergoing regular dialysis have similar complaints, such as dyspepsia. Moreover, the rate of GI bleeding is high in patients with chronic renal failure comparing with normal pop...
| Publicado en: | Medical Journal of Tabriz University of Medical Sciences & Health Services Vol. 36; no. 4; pp. 72 - 78 |
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| Autores principales: | , , , , |
| Formato: | abstract research Journal Article |
| Publicado: |
Tabriz University of Medical Sciences
Oct/Nov2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=100329199&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 100329199 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 16085671 EUW8 jtl: Medical Journal of Tabriz University of Medical Sciences & Health Services issn: 16085671 maglogo: N pubinfo: dt: Oct/Nov2014 vid: 36 iid: 4 pid: 69573 pub: Tabriz University of Medical Sciences artinfo: ui: 100329199 100329199 103869121 100329199 ppf: 72 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Helicobacter Pylori Eradication in Patients with Chronic Renal Failure. aug: au: Somi, Mohamadhosein Etemadi, Jalal Ghojazadeh, Morteza Najafi, Shahin Kanani, Parinaz affil: liver and Gastrointestinal Disease Research Center, School of Medicine,, Tabriz University of Medical Sciences, Tabriz, Iran sug: subj: Helicobacter Infections Prevention and Control Kidney Failure, Chronic Diagnosis Human Antiinflammatory Agents, Non-Steroidal Treatment Outcomes Evaluation ab: Background and Objectives: Gastrointestinal (GI) complains are common in hemodialysis patients. More than 80% of patients undergoing regular dialysis have similar complaints, such as dyspepsia. Moreover, the rate of GI bleeding is high in patients with chronic renal failure comparing with normal population. Peptic ulcer disease in nondialysis patients is associated with two main factors: a) Helicobacter Pylori (H.P) infection and b) use of Non Steroidal Anti Inflammatory Drugs (NSAIDs). The incidence rate of H.P infection in patient undergoing regular dialysis is controversial. The aim of this study was to evaluate the response to the H.P eradication therapy among patients undergoing dialysis. Materials and Methods: In this analytical study, 100 people with chronic dyspepsia with normal renal function and 80 dialyzed patients who were kidney transplant candidates with the inclusion criteria underwent upper GI endoscopy. H.P infections in those who had a positive rapid urease test or positive histology for Helicobacter and nominated for H.P treatment were enrolled. These patients received triple therapy against H.P for 2 weeks followed by 2 weeks received PPI and 4 weeks after cessation of treatment, Eradication was assessed by urease breath test (UBT). Results: The successful eradication was found in 87% and 84% of the dialysis and control groups, respectively. Both dialysis group and the control group, who received furazolidone, had 100% eradication. In dialysis patients. From 54 patients who received clarithromycin, 81.5% have been successful in. H.P eradication. In the control group, 67 patients who received clarithromycin 76.1% have been successful in. H.P eradication. Conclusion: Eradication of H.P in dialysis and control groups showed no significant differences. Meanwhile the frequency of eradication with furazolidone was significantly more than clarithromycin. pubtype: Academic Journal doctype: abstract research Journal Article ougenre: Article language: Persian refInfo: holdings: @attributes: islocal: N |
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