Pyoderma Gangrenosum: A Review of Clinical Features and Outcomes of 23 Cases Requiring Inpatient Management.

Pyoderma gangrenosum (PG) is a rare dermatological disorder characterised by the rapid progression of a painful, necrolytic ulcer. This study retrospectively identified patients who were admitted and treated for PG during a 10-year period (2003-2013). Twentythree patients were included in this study...

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Publicado en:Dermatology Research & Practice pp. 1 - 8
Autores principales: Mingwei Joel Ye, Joshua Mingsheng Ye
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 2014
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2014
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        100483193
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        10.1155/2014/461467
        100483193
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        atl: Pyoderma Gangrenosum: A Review of Clinical Features and Outcomes of 23 Cases Requiring Inpatient Management.
      aug:
        au:
          Mingwei Joel Ye
          Joshua Mingsheng Ye
        affil: Department of Dermatology, Western Hospital, Footscray, VIC 3011, Australia
      sug:
        subj:
          Pyoderma Gangrenosum Therapy
          Treatment Outcomes
          Pyoderma Gangrenosum Diagnosis
          Human
          Inpatients
          Academic Medical Centers
          Victoria
          Case Management
          Pyoderma Gangrenosum Epidemiology
          Prospective Studies
          Male
          Female
          Adult
          Middle Age
          Aged
          Aged, 80 and Over
          Treatment Duration
          Retrospective Design
          Record Review
          Descriptive Statistics
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Pyoderma gangrenosum (PG) is a rare dermatological disorder characterised by the rapid progression of a painful, necrolytic ulcer. This study retrospectively identified patients who were admitted and treated for PG during a 10-year period (2003-2013). Twentythree patients were included in this study, 16 women and seven men. The mean age at initial admission was 62.8 years (range 30 to 89 years). Lesions were localised to lower limb in 13 patients, peristomal region in four, breast in three, and upper limb in one, and two patients had PG at multiple sites. The variants of PG noted were ulcerative (18), bullous (2), vegetative (2), and pustular (1). Associated systemic diseases were observed in 11 patients (47.8%). Systemic therapies were initiated in 21 patients while two patients received topical treatments. The mean length of hospital stay was 47 days (range 5 to 243 days) and five patients died during their admissions. Seven patients required readmissions for exacerbations of their PG. Our study showed that patients admitted for treatment of PG had high morbidity and mortality. This study also highlights the importance of early and aggressive treatment of patients admitted with PG as well as treating associated systemic diseases and wound infections.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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