Physical Activity is related to Fatty Liver Marker in Obese Youth, Independently of Central Obesity or Cardiorespiratory Fitness.

Nonalcoholic fatty liver disease (NAFLD) is one of the most frequent complications associated with excess adiposity and has been identified as the leading cause of liver disease in pediatric populations worldwide. Because cardiorespiratory fitness (CRF) is related to physical activity (PA) levels, a...

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Publicado en:Journal of Sports Science & Medicine Vol. 14; no. 1; pp. 103 - 110
Autores principales: Martins, Clarice, Aires, Luisa, Freitas Júnior, Ismael, Silva, Gustavo, Silva, Alexandre, Lemos, Luís, Mota, Jorge
Formato: research tables/charts Journal Article
Publicado: Hakan Gur, Journal of Sports Science & Medicine 2015
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Hakan Gur, Journal of Sports Science & Medicine
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        atl: Physical Activity is related to Fatty Liver Marker in Obese Youth, Independently of Central Obesity or Cardiorespiratory Fitness.
      aug:
        au:
          Martins, Clarice
          Aires, Luisa
          Freitas Júnior, Ismael
          Silva, Gustavo
          Silva, Alexandre
          Lemos, Luís
          Mota, Jorge
        affil: Research Centre in Physical Activity, Health and Leisure, Porto University, Portugal
      sug:
        subj:
          Pediatric Obesity Physiopathology
          Physical Activity
          Nonalcoholic Fatty Liver Disease Physiopathology
          Alanine Aminotransferase Blood
          Oxygen Consumption
          Body Composition
          Exercise Test, Cardiopulmonary
          Accelerometry
          Abdominal Fat
          Physical Fitness
          Body Mass Index
          Waist Circumference
          Adipose Tissue Distribution
          Linear Regression
          Sample Size
          Effect Size
          P-Value
          Comparative Studies
          Descriptive Statistics
          T-Tests
          Data Analysis Software
          Multiple Linear Regression
          Child
          Adolescence
          Female
          Male
          Human
          Funding Source
          Child: 6-12 years
          Adolescent: 13-18 years
          Female
          Male
      ab: Nonalcoholic fatty liver disease (NAFLD) is one of the most frequent complications associated with excess adiposity and has been identified as the leading cause of liver disease in pediatric populations worldwide. Because cardiorespiratory fitness (CRF) is related to physical activity (PA) levels, and increased PA plays a protective role against NAFLD risk factors, the aim of this study was to analyze the association between PA and a fatty liver marker (alanine aminotransferase - ALT) in obese children and adolescents, independently of central adiposity or CRF. 131 obese children (83 girls, 7-15 year-olds) involved in a PA promotion program comprised the sample. Measurements included anthropometric and body composition evaluations (DEXA), biological measurements (venipuncture), CRF (progressive treadmill test), PA (accelerometry), and maturational stage (Tanner criteria). The associations between ALT with PA intensities, central obesity, and CRF were calculated by three different models of linear regression, adjusted for potential confounders. Level of significance was set at 95%. RESULTS: ALT was negatively associated with MVPA (β = -0.305), and CRF (β = - 0.426), and positively associated with central obesity (β=.468). After adjustment for central obesity the negative and statistically significant association between ALT with MVPA (β = -0.364) and CRF (β = -0.550) still persists while a positive and significantly correlation was shown between ALT and SB (β = 0.382). Additional adjustment for CRF (Model 3) showed significant associations for all the PA intensities analyzed including light activity. PA at different intensities is associated to a fatty liver marker in obese children and adolescents, independently of central adiposity or CRF.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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