Synthesis of optimal electrical stimulation patterns for functional motion restoration: applied to spinal cord-injured patients.

We investigated the synthesis of electrical stimulation patterns for functional movement restoration in human paralyzed limbs. We considered the knee joint system, co-activated by the stimulated quadriceps and hamstring muscles. This synthesis is based on optimized functional electrical stimulation...

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Publicado en:Medical & Biological Engineering & Computing Vol. 53; no. 3; pp. 227 - 241
Autores principales: Benoussaad, Mourad, Poignet, Philippe, Hayashibe, Mitsuhiro, Azevedo-Coste, Christine, Fattal, Charles, Guiraud, David
Formato: Journal Article
Publicado: Springer Nature Mar2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2015
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      pub: Springer Nature
      place: New York, New York
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        atl: Synthesis of optimal electrical stimulation patterns for functional motion restoration: applied to spinal cord-injured patients.
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        au:
          Benoussaad, Mourad
          Poignet, Philippe
          Hayashibe, Mitsuhiro
          Azevedo-Coste, Christine
          Fattal, Charles
          Guiraud, David
        affil: DEMAR Group, LIRMM, INRIA, University of Montpellier 2, CNRS, 860 Rue Saint Priest 34095 Montpellier Cedex 5 France
      sug:
        subj:
          Spinal Cord Physiopathology
          Spinal Cord Injuries Therapy
          Movement Physiology
          Recovery Physiology
          Models, Biological
          Muscle, Skeletal Physiopathology
          Motion
          Knee Joint Physiopathology
          Male
          Middle Age
          Young Adult
          Muscle Contraction Physiology
          Electric Stimulation Methods
          Adult
          Clinical Assessment Tools
          Scales
          Middle Aged: 45-64 years
          Adult: 19-44 years
          Male
      ab: We investigated the synthesis of electrical stimulation patterns for functional movement restoration in human paralyzed limbs. We considered the knee joint system, co-activated by the stimulated quadriceps and hamstring muscles. This synthesis is based on optimized functional electrical stimulation (FES) patterns to minimize muscular energy consumption and movement efficiency criteria. This two-part work includes a multi-scale physiological muscle model, based on Huxley's formulation. In the simulation, three synthesis strategies were investigated and compared in terms of muscular energy consumption and co-contraction levels. In the experimental validation, the synthesized FES patterns were carried out on the quadriceps-knee joint system of four complete spinal cord injured subjects. Surface stimulation was applied to all subjects, except for one FES-implanted subject who received neural stimulation. In each experimental validation, the model was adapted to the subject through a parameter identification procedure. Simulation results were successful and showed high co-contraction levels when reference trajectories were tracked. Experimental validation results were encouraging, as the desired and measured trajectories showed good agreement, with an 8.4 % rms error in a subject without substantial time-varying behavior. We updated the maximal isometric force in the model to account for time-varying behavior, which improved the average rms errors from 31.4 to 13.9 % for all subjects.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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