β-hemolytic streptococcal throat carriage and tonsillopharyngitis: a cross-sectional prevalence study in Gabon, Central Africa.
Background: Group A streptococcus (GAS) and possibly other β-hemolytic streptococci (BHS) account for a considerable morbidity and mortality burden in African populations; however, disproportionately little is known about the epidemiology of BHS in sub-Saharan Africa. This study assessed the prevale...
| Published in: | Infection Vol. 43; no. 2; pp. 177 - 184 |
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| Main Authors: | , , , , |
| Format: | research tables/charts Journal Article |
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Springer Nature
Apr2015
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=101853957&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 101853957 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03008126 NXO jtl: Infection issn: 03008126 maglogo: N pubinfo: dt: Apr2015 vid: 43 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 101853957 103781931 103781931 10.1007/s15010-014-0709-y 101853957 ppf: 177 ppct: 7 formats: fmt: @attributes: type: P tig: atl: β-hemolytic streptococcal throat carriage and tonsillopharyngitis: a cross-sectional prevalence study in Gabon, Central Africa. aug: au: Bélard, Sabine Toepfner, Nicole Arnold, Benjamin Alabi, Abraham Berner, Reinhard affil: Department of Pediatrics and Adolescent Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden Germany sug: subj: Streptococcal Infections Epidemiology Tonsillitis Immunology Pharyngitis Immunology Carrier State Risk Assessment Human Cross Sectional Studies Gabon Prospective Studies Female Male Descriptive Statistics Convenience Sample Questionnaires Physical Examination Microbiological Techniques Data Analysis Software Chi Square Test Odds Ratio Regression Infant Child, Preschool Child Adolescence Young Adult Adult Middle Age Aged Aged, 80 and Over Funding Source Infant: 1-23 months Child, Preschool: 2-5 years Child: 6-12 years Adolescent: 13-18 years Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Female Male ab: Background: Group A streptococcus (GAS) and possibly other β-hemolytic streptococci (BHS) account for a considerable morbidity and mortality burden in African populations; however, disproportionately little is known about the epidemiology of BHS in sub-Saharan Africa. This study assessed the prevalence of GAS, group G streptococcus (GGS) and group C streptococcus (GCS) carriage and tonsillopharyngitis in a Central African population. Methods: A prospective cross-sectional study was performed to assess the prevalence of and risk factors for BHS carrier status and tonsillopharyngitis in children and adults in Gabon. Results: The overall BHS carrier prevalence was 135/1,005 (13.4 %); carrier prevalence of GAS, GGS, and GCS was 58/1,005 (5.8 %), 50/1,005 (5.0 %), and 32/1,005 (3.2 %), respectively. Streptococcal carriage was associated with school and pre-school age (adjusted OR 2.65, 95 % CI 1.62-4.36, p = 0.0001 and 1.90, 95 % CI 1.14-3.17, p = 0.0141, respectively). Participants residing in urban areas were less likely carriers (OR 0.52, p = 0.0001). The point-prevalence of BHS-positive tonsillopharyngitis was 1.0 % (9/1,014) and 15.0 % (6/40) in school children with sore throat. Conclusions: Non-GAS exceeded GAS throat carriage and tonsillopharyngitis suggesting a yet underestimated role of non-GAS streptococci in BHS diseases. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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