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The peripheral blood of Aβ binding RBC as a biomarker for diagnosis of Alzheimer's disease.

Background: in vitro, it has been reported that amyloid β (Aβ) is bound to red blood cells (RBCs) and this process damages the red cell. Also, a possible relationship between RBCs and Alzheimer's disease (AD) is supported by the findings of RBC impairment in AD. Therefore, Aβ fibrils bounding RBC ar...

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Published in:Age & Ageing Vol. 44; no. 3; pp. 458 - 465
Main Authors: JIE LAN, JINPING LIU, ZHUO ZHAO, RONG XUE, NAN ZHANG, PEILAN ZHANG, PENG ZHAO, FANG ZHENG, XUGUO SUN
Format: Article
Published: Oxford University Press / USA May2015
Subjects:
Alzheimer's disease diagnosis
Erythrocytes
Biomarkers
Biological assay
Fluorescent antibody technique
Neuropsychological tests
Microscopy
Proteins
Research funding
Data analysis software
Descriptive statistics
Fluorescent dyes
Online Access:View this record in EBSCOhost