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Semisynthetic tRNA Complement Mediates in Vitro Protein Synthesis.

Genetic code expansion is a key objective of synthetic biology and protein engineering. Most efforts in this direction are focused on reassigning termination or decoding quadruplet codons. While the redundancy of genetic code provides a large number of potentially reassignable codons, their utility...

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Published in:Journal of the American Chemical Society Vol. 137; no. 13; pp. 4404 - 4414
Main Authors: Zhenling Cui, Stein, Viktor, Tnimov, Zakir, Mureev, Sergey, Alexandrov, Kirill
Format: Article
Published: American Chemical Society 4/8/2015
Subjects:
Genetic code
Synthetic biology
Protein engineering
Transfer RNA
Polypeptides
Online Access:View this record in EBSCOhost