DRD4 Genotype and the Developmental Link of Peer Social Preference with Conduct Problems and Prosocial Behavior Across Ages 9-12 Years.
The peer environment is among the most important factors for children's behavioral development. However, not all children are equally influenced by their peers, which is potentially due to their genetic make-up. The dopamine receptor D4 gene (DRD4) is a potential candidate gene that may influence ch...
| Publicado en: | Journal of Youth & Adolescence Vol. 44; no. 7; pp. 1360 - 1379 |
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| Autores principales: | , , , , |
| Formato: | Artículo |
| Publicado: |
Springer Nature
Jul2015
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=103107998&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 103107998 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00472891 JYA jtl: Journal of Youth & Adolescence issn: 00472891 maglogo: N pubinfo: dt: Jul2015 vid: 44 iid: 7 pid: 237 pub: Springer Nature artinfo: ui: 103107998 10.1007/s10964-015-0289-x ppf: 1360 ppct: 19 formats: fmt: @attributes: type: P size: 802KB tig: atl: DRD4 Genotype and the Developmental Link of Peer Social Preference with Conduct Problems and Prosocial Behavior Across Ages 9-12 Years. aug: au: Buil, J. Koot, Hans Olthof, Tjeert Nelson, Kelly Lier, Pol affil: Avera Institute for Human Genetics, 3720 W. 69th Street, Suite 200 Sioux Falls USA su: Peers Likes & dislikes Prosocial behavior Analysis of variance Behavior disorders in children Child development Socioeconomic factors Genotypes sug: subj: Peers Likes & dislikes Prosocial behavior Analysis of variance Behavior disorders in children Child development Socioeconomic factors Genotypes keyword: Conduct problems Differential susceptibility DRD4 Gene-environment interaction Peer social preference Conduct problems Differential susceptibility DRD4 Gene-environment interaction Peer social preference ab: The peer environment is among the most important factors for children's behavioral development. However, not all children are equally influenced by their peers, which is potentially due to their genetic make-up. The dopamine receptor D4 gene (DRD4) is a potential candidate gene that may influence children's susceptibility to the peer environment. In the present study, we explored whether variations in the DRD4 gene moderated the association between children's social standing in the peer group (i.e., social preference among classmates) with subsequent conduct problems and prosocial behavior among 405 (51 % females) elementary school children followed annually throughout early adolescence (ages 9-12 years). The behavioral development of children with and without the DRD4 7-repeat allele was compared. The results indicated that children who had higher positive social preference scores (i.e., who were more liked relative to disliked by their peers) showed less conduct problem development in subsequent years relative to children who had lower positive social preference scores. In contrast, children who had more negative preference scores (i.e., who were more disliked relative to liked among peers) showed more conduct problem development in subsequent years, relative to children who had less negative preference scores. However, these effects only occurred when children had a 7-repeat allele. For children who did not have a 7-repeat allele, the level of social preference was not associated with subsequent conduct problems. No evidence for gene-environment interaction effects for prosocial behavior was found. The implications for our understanding of conduct problem development and its prevention are discussed. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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