Characterization of Size-Specific Particulate Matter Emission Rates for a Simulated Medical Laser Procedure--A Pilot Study.
Prior investigation on medical laser interaction with tissue has suggested device operational parameter settings influence laser generated air contaminant emission, but this has not been systematically explored. A laboratory-based simulated medical laser procedure was designed and pilot tested to de...
| Publicado en: | Annals of Occupational Hygiene Vol. 59; no. 4; pp. 514 - 525 |
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| Autores principales: | , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Oxford University Press / USA
May2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103196259&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103196259 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00034878 JQ4 jtl: Annals of Occupational Hygiene issn: 00034878 maglogo: N pubinfo: dt: May2015 vid: 59 iid: 4 pid: 622 pub: Oxford University Press / USA artinfo: ui: 103196259 109798844 109798844 10.1093/annhyg/meu115 103196259 ppf: 514 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Characterization of Size-Specific Particulate Matter Emission Rates for a Simulated Medical Laser Procedure--A Pilot Study. aug: au: Lopez, Ramon Lacey, Steven E. Lippert, Julia F. Li C. Liu Esmen, Nurtan A. Conroy, Lorraine M. affil: Department of Environmental Health Science, Richard M. Fairbanks School of Public Health, Indiana University, 714 N. Senate Ave., Indianapolis, IN 46202, USA sug: subj: Lasers Simulations Particulate Matter Pilot Studies Data Analysis, Statistical In Vitro Studies Descriptive Statistics Data Analysis Software Microscopy, Electron, Scanning Ablation Techniques Carbon Dioxide Analysis of Variance Funding Source ab: Prior investigation on medical laser interaction with tissue has suggested device operational parameter settings influence laser generated air contaminant emission, but this has not been systematically explored. A laboratory-based simulated medical laser procedure was designed and pilot tested to determine the effect of laser operational parameters on the size-specific mass emission rate of laser generated particulate matter. Porcine tissue was lased in an emission chamber using two medical laser systems (CO2, A. = 10 600 nm; Ho:YAG, λ = 2100 nm) in a fractional factorial study design by varying three operational parameters (beam diameter, pulse repetition frequency, and power) between two levels (high and low) and the resultant plume was measured using two real-time size-selective particle counters. Particle count concentrations were converted to mass emission rates before an analysis of variance was used to determine the influence of operational parameter settings on size-specific mass emission rate. Particle shape and diameter were described for a limited number of samples by collecting particles on polycarbonate filters, and photographed using a scanning electron microscope (SEM) to examine method of particle formation. An increase in power and decrease in beam diameter led to an increase in mass emission for the Ho:YAG laser at all size ranges. For the CO2 laser, emission rates were dependent on particle size and were not statistically significant for particle ranges between 5 and 10 µm. When any parameter level was increased, emission rate of the smallest particle size range also increased. Beam diameter was the most influential variable for both lasers, and the operational parameters tested explained the most variability at the smallest particle size range. Particle shape was variable and some particles observed by SEM were likely created from mechanical methods. This study provides a foundation for future investigations to better estimate size-specific mass emission rates and particle characteristics for additional laser operational parameters in order to estimate occupational exposure, and to inform control strategies. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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