Usher Syndrome: Case Reports of Two Siblings.

Background: Usher syndrome is a rare autosomal recessive disorder characterized by congenital sensory neural deafness and progressive visual loss secondary to retinitis pigmentosa. There are three different types of Usher syndrome. Retinitis pigmentosa is the main ophthalmic manifestation shared by...

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Publicado en:Optometry & Visual Performance Vol. 3; no. 3; pp. 174 - 178
Autores principales: Prasad Sah, Raman, Gautam, Pragati, Baba Shrestha, Jyoti, Raj Joshi, Mahesh
Formato: case study pictorial tables/charts Journal Article
Publicado: Optometric Extension Program Jun2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2015
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      pub: Optometric Extension Program
      place: Lutherville Timonium, Maryland
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        atl: Usher Syndrome: Case Reports of Two Siblings.
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          Prasad Sah, Raman
          Gautam, Pragati
          Baba Shrestha, Jyoti
          Raj Joshi, Mahesh
        affil: B.P. Koirala Lions Centre for Ophthalmic Studies, Maharajgunj, Kathmandu, Nepal
      sug:
        subj:
          Usher's Syndrome
          Evoked Potentials, Visual
          Visual Acuity
          Eye Manifestations
          Tomography, Optical Coherence
          Retinitis Pigmentosa
          Siblings
      ab: Background: Usher syndrome is a rare autosomal recessive disorder characterized by congenital sensory neural deafness and progressive visual loss secondary to retinitis pigmentosa. There are three different types of Usher syndrome. Retinitis pigmentosa is the main ophthalmic manifestation shared by all three. Differences in auditory and vestibular function are the distinguishing feature. Case Reports: Two brothers, 13 and 16 years of age, presented with chief complaints of progressive diminution of vision in both eyes, especially at night. They underwent a detailed evaluation which included dilated fundus examination, cycloplegic refraction, multifocal electroretinogram (mfERG), optical coherence tomography, visual evoked potential, and Goldmann perimetry. The evaluation revealed best corrected visual acuity of 6/12 and 6/9 in each case despite the presence of bony spicules and abolished mfERG amplitudes. The clinical findings supported the diagnosis of Usher syndrome Type I. Discussion: Early detection and intervention will help preserve residual vision in these cases.
      pubtype: Academic Journal
      doctype:
        case study
        pictorial
        tables/charts
        Journal Article
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    language: English
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