Texture Feature Analysis for Computer-Aided Diagnosis on Pulmonary Nodules.

Differentiation of malignant and benign pulmonary nodules is of paramount clinical importance. Texture features of pulmonary nodules in CT images reflect a powerful character of the malignancy in addition to the geometry-related measures. This study first compared three well-known types of two-dimen...

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Publicado en:Journal of Digital Imaging Vol. 28; no. 1; pp. 99 - 116
Autores principales: Han, Fangfang, Wang, Huafeng, Zhang, Guopeng, Han, Hao, Song, Bowen, Li, Lihong, Moore, William, Lu, Hongbing, Zhao, Hong, Liang, Zhengrong
Formato: algorithm diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Feb2015
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        100631423
        10.1007/s10278-014-9718-8
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        atl: Texture Feature Analysis for Computer-Aided Diagnosis on Pulmonary Nodules.
      aug:
        au:
          Han, Fangfang
          Wang, Huafeng
          Zhang, Guopeng
          Han, Hao
          Song, Bowen
          Li, Lihong
          Moore, William
          Lu, Hongbing
          Zhao, Hong
          Liang, Zhengrong
        affil: Department of Radiology, State University of New York, Stony Brook 11794 USA
      sug:
        subj:
          Diagnosis, Computer Assisted
          Solitary Pulmonary Nodule Diagnosis
          Radiographic Image Interpretation, Computer-Assisted
          Tomography, X-Ray Computed
          Solitary Pulmonary Nodule Classification
          Comparative Studies
          Evaluation Research
          ROC Curve
          Descriptive Statistics
          P-Value
          Human
          Funding Source
      ab: Differentiation of malignant and benign pulmonary nodules is of paramount clinical importance. Texture features of pulmonary nodules in CT images reflect a powerful character of the malignancy in addition to the geometry-related measures. This study first compared three well-known types of two-dimensional (2D) texture features (Haralick, Gabor, and local binary patterns or local binary pattern features) on CADx of lung nodules using the largest public database founded by Lung Image Database Consortium and Image Database Resource Initiative and then investigated extension from 2D to three-dimensional (3D) space. Quantitative comparison measures were made by the well-established support vector machine (SVM) classifier, the area under the receiver operating characteristic curves (AUC) and the p values from hypothesis t tests. While the three feature types showed about 90 % differentiation rate, the Haralick features achieved the highest AUC value of 92.70 % at an adequate image slice thickness, where a thinner or thicker thickness will deteriorate the performance due to excessive image noise or loss of axial details. Gain was observed when calculating 2D features on all image slices as compared to the single largest slice. The 3D extension revealed potential gain when an optimal number of directions can be found. All the observations from this systematic investigation study on the three feature types can lead to the conclusions that the Haralick feature type is a better choice, the use of the full 3D data is beneficial, and an adequate tradeoff between image thickness and noise is desired for an optimal CADx performance. These conclusions provide a guideline for further research on lung nodule differentiation using CT imaging.
      pubtype: Academic Journal
      doctype:
        algorithm
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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