Relationship Between Medication Adherence and Health-Related Quality of Life in Subjects With COPD: A Systematic Review.

BACKGROUND: Various aspects of medication adherence and health-related quality of life (HRQOL) have been studied in subjects with COPD. Nevertheless, little is known about the association between these factors. The aim of this study was to undertake a systematic review of the published literature fo...

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Publicado en:Respiratory Care Vol. 60; no. 2; pp. 297 - 304
Autores principales: Ágh, Tamás, Dömötör, Péterné, Bártfai, Zoltán, Inotai, András, Fujsz, Eszter, Mészáros, Ágnes
Formato: research systematic review tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. Feb2015
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Mary Ann Liebert, Inc.
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        atl: Relationship Between Medication Adherence and Health-Related Quality of Life in Subjects With COPD: A Systematic Review.
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        au:
          Ágh, Tamás
          Dömötör, Péterné
          Bártfai, Zoltán
          Inotai, András
          Fujsz, Eszter
          Mészáros, Ágnes
        affil: Syreon Research Institute, Budapest, Hungary.
      sug:
        subj:
          Pulmonary Disease, Chronic Obstructive Psychosocial Factors
          Medication Compliance
          Quality of Life
          Human
          Systematic Review
          Medline
          Descriptive Statistics
          Female
          Male
          Middle Age
          Aged
          Middle Aged: 45-64 years
          Aged: 65+ years
          Female
          Male
      ab: BACKGROUND: Various aspects of medication adherence and health-related quality of life (HRQOL) have been studied in subjects with COPD. Nevertheless, little is known about the association between these factors. The aim of this study was to undertake a systematic review of the published literature focusing on the relationship between medication adherence and HRQOL in COPD. METHODS: A systematic literature search of English language articles was conducted in April 2013 using MEDLINE. No publication date limits were defined. All of the included studies were assessed for quality. RESULTS: Seven studies were included in the review. Three of the assessed studies found no correlation, and 3 studies described positive and 2 studies reported negative associations between medication adherence and HRQOL. The results indicate that an improved HRQOL may be a trigger for non-adherence in patients with COPD. CONCLUSIONS: The relationship between medication adherence and HRQOL may be dual. The effect of medication adherence on HRQOL might be a consequence of the effectiveness of therapy and the negative effects (ie, side effects, daily life limitation of therapy, social stigma) that it can generate. HRQOL might also influence the patterns of patients' drug use, as an increased HRQOL might trigger non-adherence. The dynamics between adherence and HRQOL might differ over time, as the negative effects of medication non-adherence might become dominant in the long term.
      pubtype: Academic Journal
      doctype:
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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