Prenatal Exposure to Maternal Cigarette Smoking and DNA Methylation: Epigenome-Wide Association in a Discovery Sample of Adolescents and Replication in an Independent Cohort at Birth through 17 Years of Age.

Background: Prenatal exposure to maternal cigarette smoking (prenatal smoke exposure) had been associated with altered DNA methylation (DNAm) at birth. Objective: We examined whether such alterations are present from birth through adolescence. Methods: We used the Infinium HumanMethylation450K BeadC...

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Bibliographic Details
Published in:Environmental Health Perspectives Vol. 123; no. 2; pp. 193 - 200
Main Authors: Lee, Ken W. K., Richmond, Rebecca, Pingzhao Hu, French, Leon, Shin, Jean, Bourdon, Celine, Reischl, Eva, Waldenberger, Melanie, Zeilinger, Sonja, Gaunt, Tom, McArdle, Wendy, Ring, Susan, Woodward, Geoff, Bouchard, Luigi, Gaudet, Daniel, Smith, George Davey, Relton, Caroline, Paus, Tomas, Pausova, Zdenka
Format: research tables/charts Journal Article
Published: National Institute of Environmental Health Sciences Feb2015
Online Access:View this record in EBSCOhost