The effects of aging on the brain activation pattern during a speech perception task: an fMRI study.
In the present study, brain activation associated with speech perception processing was examined across four groups of adult participants with age ranges between 20 and 65 years, using functional MRI (fMRI). Cognitive performance demonstrates that performance accuracy declines with age. fMRI results...
| Publicado en: | Aging Clinical & Experimental Research Vol. 27; no. 1; pp. 27 - 37 |
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| Autores principales: | , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
Feb2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103755727&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103755727 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15940667 2WMP jtl: Aging Clinical & Experimental Research issn: 15940667 maglogo: N pubinfo: dt: Feb2015 vid: 27 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 103755727 100883199 10.1007/s40520-014-0240-0 NLM24906677 103755727 ppf: 27 ppct: 10 formats: tig: atl: The effects of aging on the brain activation pattern during a speech perception task: an fMRI study. aug: au: Manan, Hanani Franz, Elizabeth Yusoff, Ahmad Mukari, Siti affil: Diagnostic Imaging and Radiotherapy Program, School of Diagnostic and Applied Health Sciences, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz 50300 Kuala Lumpur Malaysia sug: subj: Aging Brain Physiology Speech Perception Magnetic Resonance Imaging Human Male Adult Middle Age Aged Analysis of Variance Psychological Tests Repeated Measures Data Analysis Software Linear Regression T-Tests Brain Hemispheres Funding Source Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male ab: In the present study, brain activation associated with speech perception processing was examined across four groups of adult participants with age ranges between 20 and 65 years, using functional MRI (fMRI). Cognitive performance demonstrates that performance accuracy declines with age. fMRI results reveal that all four groups of participants activated the same brain areas. The same brain activation pattern was found in all activated areas (except for the right superior temporal gyrus and right middle temporal gyrus); brain activity was increased from group 1 (20-29 years) to group 2 (30-39 years). However, it decreased in group 3 (40-49 years) with further decreases in group 4 participants (50-65 years). Result also reveals that three brain areas (superior temporal gyrus, Heschl's gyrus and cerebellum) showed changes in brain laterality in the older participants, akin to a shift from left-lateralized to right-lateralized activity. The onset of this change was different across brain areas. Based on these findings we suggest that, whereas all four groups of participants used the same areas in processing, the engagement and recruitment of those areas differ with age as the brain grows older. Findings are discussed in the context of corroborating evidence of neural changes with age. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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