Identification of Helicobacter pylori infection in symptomatic patients in Surabaya, Indonesia, using five diagnostic tests.
SUMMARY The prevalence of Helicobacter pylori infection in Indonesia is controversial. We examined the H. pylori infection rate in 78 patients in a hospital in Surabaya using five different tests, including culture, histology, immunohistochemistry, rapid urease test, and urine antibody test. Further...
| Publicado en: | Epidemiology & Infection Vol. 143; no. 5; pp. 986 - 997 |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Cambridge University Press
Apr2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103764921&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103764921 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09502688 2S0 jtl: Epidemiology & Infection issn: 09502688 maglogo: N pubinfo: dt: Apr2015 vid: 143 iid: 5 pid: 15979 pub: Cambridge University Press artinfo: ui: 103764921 103764921 NLM25034254 2012925728 10.1017/S095026881400154X NLM25034254 103764921 ppf: 986 ppct: 11 formats: tig: atl: Identification of Helicobacter pylori infection in symptomatic patients in Surabaya, Indonesia, using five diagnostic tests. aug: au: Miftahussurur, M Shiota, S Suzuki, R Matsuda, M Uchida, T Kido, Y Kawamoto, F Maimunah, U Adi, P Rezkitha, Y Nasronudin Nusi, I Yamaoka, Y affil: Department of Environmental and Preventive Medicine,Oita University Faculty of Medicine,Yufu,Japan. sug: subj: Dyspepsia Microbiology Gastritis Pathology Helicobacter Infections Diagnosis Helicobacter Pylori Stomach Pathology Adolescence Adult Aged Antibodies, Bacterial Blood Antibodies, Bacterial Urine Breath Tests Culture Techniques DNA Analysis Dyspepsia Epidemiology Female Gastritis Microbiology Genotype Helicobacter Infections Epidemiology Immunohistochemistry Indonesia Male Middle Age Sequence Analysis Stomach Microbiology Urea Analysis Young Adult Adolescent: 13-18 years Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: SUMMARY The prevalence of Helicobacter pylori infection in Indonesia is controversial. We examined the H. pylori infection rate in 78 patients in a hospital in Surabaya using five different tests, including culture, histology, immunohistochemistry, rapid urease test, and urine antibody test. Furthermore, we analysed virulence factors in H. pylori strains from Indonesia. The H. pylori infection rate was only 11.5% in all patients studied, and 2.3% of Javanese patients and 18.0% of Chinese patients were infected (P = 0.01). Although severe gastritis was not observed, activity and inflammation were significantly higher in patients positive for H. pylori than in patients negative for H. pylori. Among genotypes identified from five isolated strains, cagA was found in four; two were vacA s1m1. All cagA-positive strains were oipA 'on' and iceA1 positive. We confirmed both a low H. pylori infection rate and a low prevalence of precancerous lesions in dyspeptic patients in a Surabaya hospital, which may contribute to the low incidence of gastric cancer in Indonesia. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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