The Effect of Age on Right Ventricular Diastolic Function in Healthy Subjects Undergoing Treadmill Exercise Test.
Objective There is an increasing interest for the value of right ventricle ( RV) in predicting exercise tolerance and prognosis in cardiovascular disease. However, there is relatively few data evaluating the effect of age on RV diastolic filling velocities during rest or exercise in healthy subjects...
| Publicado en: | Echocardiography Vol. 32; no. 3; pp. 436 - 443 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Mar2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103765068&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103765068 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 07422822 GSE jtl: Echocardiography issn: 07422822 maglogo: Y pubinfo: dt: Mar2015 vid: 32 iid: 3 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 103765068 101349513 10.1111/echo.12676 NLM25041471 103765068 ppf: 436 ppct: 7 formats: fmt: @attributes: type: P tig: atl: The Effect of Age on Right Ventricular Diastolic Function in Healthy Subjects Undergoing Treadmill Exercise Test. aug: au: Celik, Murat Yalcinkaya, Emre Yuksel, Uygar Cagdas Gokoglan, Yalcin Bugan, Baris Kabul, Hasan Kutsi Barcin, Cem affil: Department of Cardiology, School of Medicine, Gulhane Military Medical Academy sug: subj: Heart Ventricle, Right Physiology Exercise Test, Cardiopulmonary Diastole Physiology Age Factors Aging Physiology Human Adult Middle Age Echocardiography, Doppler Methods Echocardiography, Doppler, Pulsed Descriptive Statistics T-Tests Mann-Whitney U Test Spearman's Rank Correlation Coefficient Pearson's Correlation Coefficient Data Analysis Software Female Male Young Adult Aged Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Female Male ab: Objective There is an increasing interest for the value of right ventricle ( RV) in predicting exercise tolerance and prognosis in cardiovascular disease. However, there is relatively few data evaluating the effect of age on RV diastolic filling velocities during rest or exercise in healthy subjects. Methods A total of 54 healthy subjects were enrolled in this study. Patients were divided into 2 groups according to their age: Group 1 (≤45-years-old) and Group 2 (>45-years-old). A treadmill exercise test was performed using modified Bruce protocol. Conventional pulsed-wave Doppler and tissue Doppler velocities were obtained both at rest and immediately after the end of exercise, respectively. Results In the overall analysis, tricuspid flow Doppler analysis showed a significant increase in A-wave velocity, less marked rise in E-wave velocity, decreased E/A ratio and decreased E-wave deceleration time ( EDT) with exercise. Tissue Doppler analysis revealed increased Aa velocity, decreased in Ea/Aa ratio and IVRT. No significant change was observed in Ea velocity and E/Ea ratio with exercise. Although diastolic velocities changed significantly with exercise, systolic velocities did not. Cardiac response to exercise differed slightly in the older subjects compared to younger ones. The older subjects were more likely to have a reduced mean rate of RV filling for the second half of diastole from baseline to peak exercise. Conclusion To distinguish normal physiological changes due to aging from those of pathologic conditions may provide benefits while evaluating patients with known or suspected cardiovascular disease. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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