Assessment of pharmacokinetic drug-drug interaction between pradigastat and acetaminophen in healthy subjects.

Purpose: The purpose of this study was to evaluate the effect of pradigastat, a diacylglycerol acyltransferase-1 inhibitor, on the pharmacokinetics of acetaminophen, a gastric emptying marker. Methods: Twenty-five healthy subjects were enrolled and received 1000 mg acetaminophen with meal in period...

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Publicado en:European Journal of Clinical Pharmacology Vol. 71; no. 4; pp. 425 - 433
Autores principales: Ayalasomayajula, Surya, Meyers, Dan, Koo, Phillip, Salunke, Atish, Majumdar, Tapan, Rebello, Sam, Sunkara, Gangadhar, Chen, Jin
Formato: pictorial research tables/charts Journal Article
Publicado: Springer Nature Apr2015
Acceso en línea:Ver este registro en EBSCOhost