Successful Face Recognition is Associated with Increased Prefrontal Cortex Activation in Autism Spectrum Disorder.

This study examines whether deficits in visual information processing in autism-spectrum disorder (ASD) can be offset by the recruitment of brain structures involved in selective attention. During functional MRI, 12 children with ASD and 19 control participants completed a selective attention one-ba...

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Publicado en:Journal of Autism & Developmental Disorders Vol. 45; no. 4; pp. 902 - 911
Autores principales: Herrington, John, Riley, Meghan, Grupe, Daniel, Schultz, Robert
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Apr2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2015
      vid: 45
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      pub: Springer Nature
      place: New York, New York
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        atl: Successful Face Recognition is Associated with Increased Prefrontal Cortex Activation in Autism Spectrum Disorder.
      aug:
        au:
          Herrington, John
          Riley, Meghan
          Grupe, Daniel
          Schultz, Robert
        affil: Children's Hospital of Philadelphia, 3535 Market Street, Suite 860 Philadelphia 19104 USA
      sug:
        subj:
          Autism Spectrum Disorder Symptoms
          Recognition (Psychology)
          Cerebral Cortex Physiology
          Physiological Processes Evaluation
          Face
          Human
          Funding Source
          Magnetic Resonance Imaging
          Psychological Tests
          Clinical Assessment Tools
          Cerebral Cortex Radiography
          Paradigms
          Practice Guidelines
          Interview Guides
          Scales
          Interviews
          Matched Case Control
          Child
          Adolescence
          Intelligence Tests
          Data Analysis Software
          Analysis of Variance
          Pearson's Correlation Coefficient
          Behavioral Research
          Child: 6-12 years
          Adolescent: 13-18 years
      ab: This study examines whether deficits in visual information processing in autism-spectrum disorder (ASD) can be offset by the recruitment of brain structures involved in selective attention. During functional MRI, 12 children with ASD and 19 control participants completed a selective attention one-back task in which images of faces and houses were superimposed. When attending to faces, the ASD group showed increased activation relative to control participants within multiple prefrontal cortex areas, including dorsolateral prefrontal cortex (DLPFC). DLPFC activation in ASD was associated with increased response times for faces. These data suggest that prefrontal cortex activation may represent a compensatory mechanism for diminished visual information processing abilities in ASD.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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