Relation of Exercise Capacity With Lung Volumes Before and After 6-Minute Walk Test in Subjects With COPD.

INTRODUCTION: There is growing evidence that exercise-induced variation in lung volumes is an important source of ventilatory limitation and is linked to exercise intolerance in COPD. The aim of this study was to compare the correlations of walk distance and lung volumes measured before and after a...

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Publicado en:Respiratory Care Vol. 59; no. 11; pp. 1687 - 1696
Autores principales: Wibmer, Thomas, Rüdiger, Stefan, Kropf-Sanchen, Cornelia, Stoiber, Kathrin M., Rottbauer, Wolfgang, Schumann, Christian
Formato: research tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. Nov2014
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Relation of Exercise Capacity With Lung Volumes Before and After 6-Minute Walk Test in Subjects With COPD.
      aug:
        au:
          Wibmer, Thomas
          Rüdiger, Stefan
          Kropf-Sanchen, Cornelia
          Stoiber, Kathrin M.
          Rottbauer, Wolfgang
          Schumann, Christian
        affil: Department of Internal Medicine II, University Hospital of Ulm, Ulm, Germany
      sug:
        subj:
          Pulmonary Disease, Chronic Obstructive
          Lung Volume Measurements
          Exercise Tolerance Evaluation
          Human
          Clinical Assessment Tools
          Pearson's Correlation Coefficient
          Record Review
          Spirometry
          Practice Guidelines
          Male
          Female
          Middle Age
          Aged
          Two-Tailed Test
          Descriptive Statistics
          Data Analysis Software
          Step-Wise Multiple Regression
          Correlational Studies
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: INTRODUCTION: There is growing evidence that exercise-induced variation in lung volumes is an important source of ventilatory limitation and is linked to exercise intolerance in COPD. The aim of this study was to compare the correlations of walk distance and lung volumes measured before and after a 6-min walk test (6MWT) in subjects with COPD. METHODS: Forty-five subjects with stable COPD (mean pre-bronchodilator FEV1: 47 ± 18% predicted) underwent a 6MWT. Body plethysmography was performed immediately pre- and post-6MWT. RESULTS: Correlations were generally stronger between 6-min walk distance and post-6MWT lung volumes than between 6-min walk distance and pre-6MWT lung volumes, except for FEV1. These differences in Pearson correlation coefficients were significant for residual volume expressed as percent of total lung capacity (-0.67 vs -0.58, P = .043), percent of predicted residual volume expressed as percent of total lung capacity (-0.68 vs -0.59, P = .026), inspiratory vital capacity (0.65 vs 0.54, P = .019), percent of predicted inspiratory vital capacity (0.49 vs 0.38, P = .037), and percent of predicted functional residual capacity (0.62 vs 0.47, P = .023). CONCLUSIONS: In subjects with stable COPD, lung volumes measured immediately after 6MWT are more closely related to exercise limitation than baseline lung volumes measured before 6MWT, except for FEV1. Therefore, pulmonary function testing immediately after exercise should be included in future studies on COPD for the assessment of exercise-induced ventilatory constraints to physical performance that cannot be adequately assessed from baseline pulmonary function testing at rest.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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