The role of natural antisense transcripts in the pathogenesis of nervous system diseases.
Mammalian genomes encode numerous natural antisense transcripts (NATs). These antisense transcripts are now recognized as an important component of molecular mechanisms involved in the regulation of gene expression. NATs are particularly prevalent in the mammalian nervous system. The importance of N...
| Publicado en: | Chinese Journal of Contemporary Neurology & Neurosurgery Vol. 15; no. 3; pp. 240 - 245 |
|---|---|
| Autores principales: | , |
| Formato: | abstract research Journal Article |
| Publicado: |
Chinese Journal of Contemporary Neurology & Neurosurgery
3/25/2015
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103778723&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103778723 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 16726731 FDQ6 jtl: Chinese Journal of Contemporary Neurology & Neurosurgery issn: 16726731 maglogo: N pubinfo: dt: 3/25/2015 vid: 15 iid: 3 pid: 80951 pub: Chinese Journal of Contemporary Neurology & Neurosurgery artinfo: ui: 103778723 101746225 10.3969/j.issn.1672-6731.2015.03.014 103778723 ppf: 240 ppct: 5 formats: fmt: @attributes: type: P tig: atl: The role of natural antisense transcripts in the pathogenesis of nervous system diseases. aug: au: XIANG Lei SONG Yi-jun affil: Department of Neurology, Tianjin Huanhu Hospital, Tianjin 300060, China sug: subj: RNA Physiology Nervous System Diseases Physiopathology Neurology Neurosurgery Human Biochemistry Nervous System Diseases Diagnosis Genome ab: Mammalian genomes encode numerous natural antisense transcripts (NATs). These antisense transcripts are now recognized as an important component of molecular mechanisms involved in the regulation of gene expression. NATs are particularly prevalent in the mammalian nervous system. The importance of NATs in the normal functioning of nervous system is becoming increasingly evident. They are not only involved in neuronal differentiation, myelination and ion channel regulation, but also in advanced cognitive processes, such as synapse plasticity and memory formation. This paper focuses on the potential involvement of NATs in various neurodegenerative disorders. pubtype: Academic Journal doctype: abstract research Journal Article ougenre: Article language: Chinese refInfo: holdings: @attributes: islocal: N |
|---|