Epidemiology and outcome of systemic infections due to saprochaete capitata: case report and review of the literature.

A case of systemic infection due to Saprochaete capitata in a patient with chronic lymphocytic leukemia is described. A review of the literature was conducted to identify all reported cases of this infection described between 1977 and August 2013. One hundred and four cases (included the present one...

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Publicado en:Infection Vol. 43; no. 2; pp. 211 - 216
Autores principales: Mazzocato, S., Marchionni, E., Fothergill, A., Sutton, D., Staffolani, S., Gesuita, R., Skrami, E., Fiorentini, A., Manso, E., Barchiesi, F.
Formato: case study pictorial research systematic review tables/charts Journal Article
Publicado: Springer Nature Apr2015
Acceso en línea:Ver este registro en EBSCOhost
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        10.1007/s15010-014-0668-3
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        atl: Epidemiology and outcome of systemic infections due to saprochaete capitata: case report and review of the literature.
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          Mazzocato, S.
          Marchionni, E.
          Fothergill, A.
          Sutton, D.
          Staffolani, S.
          Gesuita, R.
          Skrami, E.
          Fiorentini, A.
          Manso, E.
          Barchiesi, F.
        affil: Clinica Malattie Infettive, Università Politecnica delle Marche, Azienda Ospedaliero-Universitaria, Ospedali Riuniti Umberto I-Lancisi-Salesi, Via Conca, Torrette di Ancona 60020 Ancona Italy
      sug:
        subj:
          Leukemia, Lymphocytic, Chronic
          Shock, Septic Etiology
          Multiple Organ Dysfunction Syndrome Diagnosis
          Human
          Male
          Aged
          Bone Marrow Examination
          Biopsy
          Microscopy
          Peritonitis
          Systematic Review
          PubMed
          Aged: 65+ years
          Male
      ab: A case of systemic infection due to Saprochaete capitata in a patient with chronic lymphocytic leukemia is described. A review of the literature was conducted to identify all reported cases of this infection described between 1977 and August 2013. One hundred and four cases (included the present one) were identified. The median age of the patients was 56 years and 56 % were males. Comorbidities included acute myeloid leukemia (52 %), acute lymphoid leukemia (22 %), other hematological malignancies (13 %) and non-hematological diseases (9 %). At the time of the infection, 82 % of the patients were neutropenic. In 75 % of the cases, the yeast was isolated from blood culture, in 25 % from other sterile sites. Empirical treatment was done in 36 % of the cases. Fifty-eight percent of the individual cases were treated with a combination or a sequential antifungal therapy. Amphotericin B was the antifungal drug most commonly used, followed by voriconazole and itraconazole. The overall crude mortality was 60 %. Saprochaete capitata causes life-threatening infections in neutropenic patients. This comprehensive literature review may help the clinician to optimize the management of this rare infection.
      pubtype: Academic Journal
      doctype:
        case study
        pictorial
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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