Lowered Parasympathetic Activity in Apparently Healthy Subjects with Self-Reported Symptoms of Pain: Preliminary Results from a Pilot Study.

Objectives The aim was to evaluate differences in the autonomic nervous system ( ANS) activity, indexed by heart rate variability ( HRV) in apparently healthy subjects with self-reported symptoms of pain ( SRSP) within an exploratory analysis. Methods HRV data from 14 apparently healthy male individ...

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Publicado en:Pain Practice Vol. 15; no. 4; pp. 314 - 319
Autores principales: Koenig, Julian, Jarczok, Marc N., Ellis, Robert J., Warth, Marco, Hillecke, Thomas K., Thayer, Julian F.
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Apr2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2015
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/papr.12177
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        atl: Lowered Parasympathetic Activity in Apparently Healthy Subjects with Self-Reported Symptoms of Pain: Preliminary Results from a Pilot Study.
      aug:
        au:
          Koenig, Julian
          Jarczok, Marc N.
          Ellis, Robert J.
          Warth, Marco
          Hillecke, Thomas K.
          Thayer, Julian F.
        affil: School of Therapeutic Sciences, SRH University Heidelberg
      sug:
        subj:
          Autonomic Nervous System Physiology
          Heart Rate Variability
          Self Report
          Pain Symptoms
          Parasympathetic Nervous System Physiopathology
          Pilot Studies
          Association (Research)
          Human
          Male
          Adult
          Data Analysis Software
          Descriptive Statistics
          Pearson's Correlation Coefficient
          P-Value
          Confidence Intervals
          Odds Ratio
          T-Tests
          Analysis of Variance
          Adult: 19-44 years
          Male
      ab: Objectives The aim was to evaluate differences in the autonomic nervous system ( ANS) activity, indexed by heart rate variability ( HRV) in apparently healthy subjects with self-reported symptoms of pain ( SRSP) within an exploratory analysis. Methods HRV data from 14 apparently healthy male individuals were analyzed to address potential differences in subjects with and without SRSP. SRSP was assessed using the four pain-related items from the symptom checklist (SCL-90R). Subjects were stratified based on the presence of SRSP. Results Parasympathetic activity, indexed by pNN50, RMSSD, and high frequency ( HF) spectrum of HRV, was lower in subjects with SRSP. Low frequency ( LF) HRV and the LF/ HF ratio were greater in subjects with SRSP. However, analysis of variance revealed no significant differences between the groups. Pearson correlations showed a correlation of pNN50, HF, LF, and LF/ HF ratio and the presence and frequency of SRSP. Measures of parasympathetic activity (pNN50 and HF) were inversely associated with more SRSP, indicating that subjects with more frequent SRSP show decreased parasympathetic activity. Conclusions Consistent with evidence on changes in HRV in patients with clinical conditions of chronic or recurrent pain, this is the first study to show that healthy individuals who report symptoms of pain may have lower parasympathetic activity revealed by measures of HRV.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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