International standards for neurological classification of spinal cord injury: classification skills of clinicians versus computational algorithms.

Study design:This is a retrospective analysis.Objectives:The objective of this study was to describe and quantify the discrepancy in the classification of the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) by clinicians versus a validated computational algori...

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Publicado en:Spinal Cord Vol. 53; no. 4; pp. 324 - 332
Autores principales: Schuld, C, Franz, S, van Hedel, H J A, Moosburger, J, Maier, D, Abel, R, van de Meent, H, Curt, A, Weidner, N, Rupp, R
Formato: research tables/charts Journal Article
Publicado: Springer Nature Apr2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2015
      vid: 53
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      pub: Springer Nature
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        10.1038/sc.2014.221
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        atl: International standards for neurological classification of spinal cord injury: classification skills of clinicians versus computational algorithms.
      aug:
        au:
          Schuld, C
          Franz, S
          van Hedel, H J A
          Moosburger, J
          Maier, D
          Abel, R
          van de Meent, H
          Curt, A
          Weidner, N
          Rupp, R
        affil: Spinal Cord Injury Center, Heidelberg University Hospital, Heidelberg, Germany
      sug:
        subj:
          Spinal Cord Injuries Classification
          Human
          Retrospective Design
          Quantitative Studies
          Algorithms
          Expert Clinicians
          Multicenter Studies
          Switzerland
          France
          Germany
          Netherlands
          Minimum Data Set
          Physicians
          Interns and Residents
          Funding Source
      ab: Study design:This is a retrospective analysis.Objectives:The objective of this study was to describe and quantify the discrepancy in the classification of the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) by clinicians versus a validated computational algorithm.Settings:European Multicenter Study on Human Spinal Cord Injury (EMSCI).Methods:Fully documented ISNCSCI data sets from EMSCI's first years (2003-2005) classified by clinicians (mostly spinal cord medicine residents, who received in-house ISNCSCI training by senior SCI physicians) were computationally reclassified. Any differences in the scoring of sensory and motor levels, American Spinal Injury Association Impairment Scale (AIS) or the zone of partial preservation (ZPP) were quantified.Results:Four hundred and twenty ISNCSCI data sets were evaluated. The lowest agreement was found in motor levels (right: 62.1%, P=0.002; left: 61.8%, P=0.003), followed by motor ZPP (right: 81.6%, P=0.74; left 80.0%, P=0.27) and then AIS (83.4%, P=0.001). Sensory levels and sensory ZPP showed the best concordance (right sensory level: 90.8%, P=0.66; left sensory level: 90.0%, P=0.30; right sensory ZPP: 91.0%, P=0.18; left sensory ZPP: 92.2%, P=0.03). AIS B was most often misinterpreted as AIS C and vice versa (AIS B as C: 29.4% and AIS C as B: 38.6%).Conclusion:Most difficult classification tasks were the correct determination of motor levels and the differentiation between AIS B and AIS C/D. These issues should be addressed in upcoming ISNCSCI revisions. Training is strongly recommended to improve classification skills for clinical practice, as well as for clinical investigators conducting spinal cord studies.Sponsorship:This study is partially funded by the International Foundation for Research in Paraplegia, Zurich, Switzerland.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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