Performance of an Automatic Arrhythmia Classification Algorithm: Comparison to the ALTITUDE Electrophysiologist Panel Adjudications.
Introduction: Adjudication of thousands of implantable cardioverter defibrillator (ICD)-treated arrhythmia episodes is labor intensive and, as a result, is most often left undone. The objective of this study was to evaluate an automatic classification algorithm for adjudication of ICD-treated arrhyt...
| Published in: | Pacing & Clinical Electrophysiology Vol. 37; no. 7; pp. 889 - 900 |
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| Main Authors: | , , , , , , , , , |
| Format: | research tables/charts tracings Journal Article |
| Published: |
Wiley-Blackwell
Jul2014
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103788744&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103788744 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01478389 4F8 jtl: Pacing & Clinical Electrophysiology issn: 01478389 maglogo: Y pubinfo: dt: Jul2014 vid: 37 iid: 7 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 103788744 102088132 10.1111/pace.12367 NLM24527748 103788744 ppf: 889 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Performance of an Automatic Arrhythmia Classification Algorithm: Comparison to the ALTITUDE Electrophysiologist Panel Adjudications. aug: au: Mahajan, Deepa Yanting Dong Saxon, Leslie A. Yong-Mei Cha Gilliam Iii, Francis Roosevelt Asirvatham, Samuel J. Cesario, David A. Jones, Paul W. Seth, Milan Powell, Brian D. affil: Boston Scientific, St. Paul, Minnesota sug: subj: Arrhythmia Classification Algorithms Evaluation Electrophysiology Defibrillators, Implantable Human Descriptive Statistics Odds Ratio Confidence Intervals Funding Source Heart Function Tests ab: Introduction: Adjudication of thousands of implantable cardioverter defibrillator (ICD)-treated arrhythmia episodes is labor intensive and, as a result, is most often left undone. The objective of this study was to evaluate an automatic classification algorithm for adjudication of ICD-treated arrhythmia episodes. Methods: The algorithm uses a machine learning algorithm and was developed using 776 arrhythmia episodes. The algorithm was validated on 131 dual-chamber ICD shock episodes from 127 patients adjudicated by seven electrophysiologists (EPs). Episodes were classified by panel consensus as ventricular tachycardia/ventricular fibrillation (VT/VF) or non-VT/VF, with the resulting classifications used as the reference. Subsequently, each episode electrogram (EGM) data was randomly assigned to three EPs without the atrial lead information, and to three EPs with the atrial lead information. Those episodes were also classified by the automatic algorithm with and without atrial information. Agreement with the reference was compared between the three EPs consensus group and the algorithm. Results: The overall agreement with the reference was similar between three-EP consensus and the algorithm for both with atrial EGM (94% vs 95%, P = 0.87) and without atrial EGM (90% vs 91%, P = 0.91). The odds of accurate adjudication, after adjusting for covariates, did not significantly differ between the algorithm and EP consensus (odds ratio 1.02, 95% confidence interval: 0.97-1.06). Conclusions: This algorithm performs at a level comparable to an EP panel in the adjudication of arrhythmia episodes treated by both dual- and single-chamber ICDs. This type of algorithm has the potential for automated analysis of clinical ICD episodes, and adjudication of EGMs for research studies and quality analyses. pubtype: Academic Journal doctype: research tables/charts tracings Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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