Advanced Mechanical Ventilatory Constraints During Incremental Exercise in Class III Obese Male Subjects.

BACKGROUND: We investigated the role of mechanical ventilatory constraints in obese class III subjects during incremental exercise. METHODS: We examined 14 control subjects (body mass index [BMI], 23.6 ± 3.2 kg/m2), 15 obese class II subjects (BMI, 37.2 ± 4.5 kg/m2), and 17 obese class III subjects...

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Publicado en:Respiratory Care Vol. 60; no. 4; pp. 549 - 561
Autores principales: Chlif, Mehdi, Temfemo, Abdou, Keochkerian, David, Choquet, Dominique, Chaouachi, Anis, Ahmaidi, Said
Formato: research tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. Apr2015
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Mary Ann Liebert, Inc.
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        atl: Advanced Mechanical Ventilatory Constraints During Incremental Exercise in Class III Obese Male Subjects.
      aug:
        au:
          Chlif, Mehdi
          Temfemo, Abdou
          Keochkerian, David
          Choquet, Dominique
          Chaouachi, Anis
          Ahmaidi, Said
        affil: Sport Science Department, Picardie Jules Verne University, F-80025 Amiens Cedex, France; Tunisian Research Laboratory Sport Performance Optimization, National Center of Medicine and Science in Sports, Tunis, Tunisia
      sug:
        subj:
          Respiration, Artificial
          Obesity
          Exercise Tolerance
          Case Control Studies
          Human
          Male
          Adult
          Middle Age
          Descriptive Statistics
          Data Analysis Software
          One-Way Analysis of Variance
          T-Tests
          Pearson's Correlation Coefficient
          P-Value
          Post Hoc Analysis
          Body Mass Index
          Waist-Hip Ratio
          Exertion
          Lung Volume Measurements
          Dyspnea Complications
          Respiratory Mechanics
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
      ab: BACKGROUND: We investigated the role of mechanical ventilatory constraints in obese class III subjects during incremental exercise. METHODS: We examined 14 control subjects (body mass index [BMI], 23.6 ± 3.2 kg/m2), 15 obese class II subjects (BMI, 37.2 ± 4.5 kg/m2), and 17 obese class III subjects (BMI, 53.4 ± 6.8 kg/m2). All subjects performed pulmonary function tests and maximal inspiratory pressure at rest, ventilatory parameters, flow-volume loops, and rated perceived exertion and breathlessness during exercise. RESULTS: All subjects had normal pulmonary function. Obesity resulted in increased minute ventilation for a given submaximal work rate, although minute ventilation during peak exercise was lowest in the obese class III subjects. End-expiratory lung volume was significantly lower in the obese subjects at rest and during exercise at the ventilatory threshold but not during peak exercise. During heavy-to-peak exercise, the obese subjects increased their end-expiratory lung volume, whereas the control group continued to decrease this parameter. Compared with controls, end-inspiratory lung volume was significantly lower in obese class II subjects and obese class III subjects at rest and at the ventilatory threshold but not during peak exercise. At maximal exercise, obese class III subjects had a greater end-inspiratory lung volume than obese class II subjects and controls. Obese class III subjects displayed a greater expiratory air flow limitation at rest, at the ventilatory threshold, and during peak exercise than both controls and obese class II subjects. CONCLUSIONS: Mechanical ventilatory constraints increase progressively with degrees of obesity, contributing to exercise limitation in obese subjects.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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