Assessment of Perianesthesic Data in Subjects Undergoing Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration.

BACKGROUND: Transbronchial needle aspiration using endobronchial ultrasonography (EBUS-TBNA), a new minimally invasive diagnostic procedure, has been used to evaluate intrathoracic lymph nodes. It has been reported that EBUS-TBNA can be performed safely under sedation and provides a high level of pa...

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Publicado en:Respiratory Care Vol. 60; no. 4; pp. 567 - 577
Autores principales: Sazak, Hilal, Tunç, Mehtap, Alagöz, Ali, Pehlivanoğlu, Polat, Demirci, Nilgün Yılmaz, Alıcı, İbrahim O, Yılmaz, Aydın
Formato: research tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. Apr2015
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Assessment of Perianesthesic Data in Subjects Undergoing Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration.
      aug:
        au:
          Sazak, Hilal
          Tunç, Mehtap
          Alagöz, Ali
          Pehlivanoğlu, Polat
          Demirci, Nilgün Yılmaz
          Alıcı, İbrahim O
          Yılmaz, Aydın
        affil: Department of Anesthesiology and Reanimation, Ataturk Chest Diseases and Thoracic Surgery Education and Research Hospital, Ankara, Turkey
      sug:
        subj:
          Bronchoscopy Methods
          Biopsy, Needle
          Ultrasonography
          Anesthetics Administration and Dosage
          Human
          Female
          Male
          Descriptive Statistics
          Data Analysis Software
          T-Tests
          One-Way Analysis of Variance
          Kruskal-Wallis Test
          Mann-Whitney U Test
          Pearson's Correlation Coefficient
          Chi Square Test
          Fisher's Exact Test
          Spearman's Rank Correlation Coefficient
          P-Value
          Confidence Intervals
          Odds Ratio
          Post Hoc Analysis
          Adult
          Middle Age
          Aged
          Retrospective Design
          Minimally Invasive Procedures
          Propofol Drug Effects
          Ketamine Drug Effects
          Midazolam Drug Effects
          Anesthesia Recovery
          Patient Satisfaction
          Sedation Psychosocial Factors
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Female
          Male
      ab: BACKGROUND: Transbronchial needle aspiration using endobronchial ultrasonography (EBUS-TBNA), a new minimally invasive diagnostic procedure, has been used to evaluate intrathoracic lymph nodes. It has been reported that EBUS-TBNA can be performed safely under sedation and provides a high level of patient satisfaction. We aimed to describe perianesthetic data, and compare results regarding the agents of subjects undergoing EBUS-TBNA under deep sedation. METHODS: After ethics committee approval, perianesthetic data of 571 subjects undergoing EBUS-TBNA were analyzed retrospectively. Data were collected from anesthesia evaluation and observation forms. Four groups received anesthesia in the operating room as follows: propofol-midazolam (group PM), propofol-ketamine (group PK), propofol-ketamine-midazolam (group PKM), or propofol (group P). Dosage, number of anesthetic injection, hemodynamic variables, recovery time, complications, and patient satisfaction were also recorded. RESULTS: Propofol consumption was higher in groups P and PM compared with groups PK and PKM. Midazolam requirement was higher in group PM than in group PKM. Recovery time was shorter in group P compared with groups PK, PM, and PKM. It was also shorter in groups PK and PM compared with group PKM. All of these differences were statistically significant. Temporary desaturation (n = 41; 7%) and increased blood pressure (n = 78; 14%) were predominant complications. In groups PK and PKM, risk of developing hypertension was higher than in groups PM and P (P < .001). The percentage of subjects satisfied with the procedure was 99%. CONCLUSIONS: Independent from the sedative agent, deep sedation can be safe, and provide high patient satisfaction during EBUS-TBNA. The combination of ketamine with propofol or midazolam required lower doses of these anesthetics. However, the incidence of increased blood pressure was higher in groups administered ketamine. Recovery time was the shortest in group P, and the longest in group PKM. There was no relation between recovery time and total dose of anesthetics or presence of chronic disease.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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