Applying Machine Learning to Facilitate Autism Diagnostics: Pitfalls and Promises.

Machine learning has immense potential to enhance diagnostic and intervention research in the behavioral sciences, and may be especially useful in investigations involving the highly prevalent and heterogeneous syndrome of autism spectrum disorder. However, use of machine learning in the absence of...

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Publicado en:Journal of Autism & Developmental Disorders Vol. 45; no. 5; pp. 1121 - 1137
Autores principales: Bone, Daniel, Goodwin, Matthew, Black, Matthew, Lee, Chi-Chun, Audhkhasi, Kartik, Narayanan, Shrikanth
Formato: algorithm research tables/charts Journal Article
Publicado: Springer Nature May2015
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Applying Machine Learning to Facilitate Autism Diagnostics: Pitfalls and Promises.
      aug:
        au:
          Bone, Daniel
          Goodwin, Matthew
          Black, Matthew
          Lee, Chi-Chun
          Audhkhasi, Kartik
          Narayanan, Shrikanth
        affil: Signal Analysis & Interpretation Laboratory (SAIL), University of Southern California, 3710 McClintock Ave. Los Angeles 90089 USA
      sug:
        subj:
          Autism Spectrum Disorder Diagnosis
          Diagnosis, Computer Assisted In Infancy and Childhood
          Algorithms Utilization
          Human
          Signal Processing, Computer Assisted
          Checklists
          Interview Guides
          Conceptual Framework
          Experimental Studies
          Child, Preschool
          Child
          Replication Studies
          Diagnostic Errors
          Child, Preschool: 2-5 years
          Child: 6-12 years
      ab: Machine learning has immense potential to enhance diagnostic and intervention research in the behavioral sciences, and may be especially useful in investigations involving the highly prevalent and heterogeneous syndrome of autism spectrum disorder. However, use of machine learning in the absence of clinical domain expertise can be tenuous and lead to misinformed conclusions. To illustrate this concern, the current paper critically evaluates and attempts to reproduce results from two studies (Wall et al. in Transl Psychiatry 2(4):e100, ; PloS One 7(8), ) that claim to drastically reduce time to diagnose autism using machine learning. Our failure to generate comparable findings to those reported by Wall and colleagues using larger and more balanced data underscores several conceptual and methodological problems associated with these studies. We conclude with proposed best-practices when using machine learning in autism research, and highlight some especially promising areas for collaborative work at the intersection of computational and behavioral science.
      pubtype: Academic Journal
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        research
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      ougenre: Article
    language: English
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