Pharmacokinetics of intravenous telavancin in healthy subjects with varying degrees of renal impairment.

Purpose: We evaluated the effect of renal impairment (RI) on the pharmacokinetics of telavancin and hydroxypropylbetadex (excipient in the telavancin drug product). Methods: Adults with normal, mild, moderate or severe RI or end-stage renal disease (ESRD) receiving haemodialysis were included in two...

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Publicado en:European Journal of Clinical Pharmacology Vol. 71; no. 6; pp. 707 - 715
Autores principales: Worboys, Philip, Wong, Shekman, Barriere, Steven
Formato: equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Jun2015
Acceso en línea:Ver este registro en EBSCOhost