The use of optical spectroscopy for in vivo detection of cervical pre-cancer.
In order to investigate the effectiveness of optical spectroscopy for in vivo diagnosis of cervical pre-cancerous conditions, a series of published studies are surveyed. The six optical technologies investigated include fluorescence spectroscopy, reflectance spectroscopy, and their combination using...
| Publicado en: | Lasers in Medical Science Vol. 29; no. 2; pp. 831 - 846 |
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| Autores principales: | , , , |
| Formato: | research review Journal Article |
| Publicado: |
Springer Nature
Mar2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103813247&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103813247 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 02688921 O4P jtl: Lasers in Medical Science issn: 02688921 maglogo: N pubinfo: dt: Mar2014 vid: 29 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 103813247 NLM23467754 2012508068 10.1007/s10103-013-1288-3 NLM23467754 103813247 ppf: 831 ppct: 15 formats: tig: atl: The use of optical spectroscopy for in vivo detection of cervical pre-cancer. aug: au: Hariri Tabrizi, Sanaz Aghamiri, S Mahmoud Reza Farzaneh, Farah Sterenborg, Henricus J C M affil: Department of Radiation Medicine Engineering, Shahid Beheshti University, Tehran, Iran, S_HaririTabrizi@sbu.ac.ir. sug: subj: Optics Methods Precancerous Conditions Pathology Spectrum Analysis Methods Cervix Neoplasms Pathology Algorithms Female Human Precancerous Conditions Diagnosis Sample Size Sensitivity and Specificity Spectrometry, Fluorescence Methods Cervix Neoplasms Diagnosis Female ab: In order to investigate the effectiveness of optical spectroscopy for in vivo diagnosis of cervical pre-cancerous conditions, a series of published studies are surveyed. The six optical technologies investigated include fluorescence spectroscopy, reflectance spectroscopy, and their combination using point probe or multispectral imaging approaches. Searching in the well-known databases, the most recent published works were sought out. Various aspects of the studies were evaluated including the details of the technology used, the pathologic threshold for tissue classification and the gold standard, the study population and prevalence of disease in this population, the method of measurement, the number of clinicians involved in the study, the classification and validation algorithms, and the performance in terms of sensitivity, specificity and, when available, the area under the receiver operating characteristic curve. Forty-four studies conducted from 1994 to 2012 were evaluated. The data are gathered in two comprehensive tables, and five illustrations are provided to simplify a comparison between studies from different points of view. There is a broad band of studies from small pilot studies through phase III clinical trials. Among the reviewed articles, only three factors were found to influence the performance of the optical spectroscopy studies. Multispectral approaches show higher specificity than the point probe approaches (p = 0.001). The use of acetic acid before measurement and prevalence of disease among the studied population, also, have an impact on the sensitivity and specificity of the studies (p < 0.05), respectively. pubtype: Academic Journal doctype: meta analysis research review Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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