Brain functional connectivity during the experience of thought blocks in schizophrenic patients with persistent auditory verbal hallucinations: an EEG study.
Thought blocks (TBs) are characterized by regular interruptions in the stream of thought. Outward signs are abrupt and repeated interruptions in the flow of conversation or actions while subjective experience is that of a total and uncontrollable emptying of the mind. In the very limited bibliograph...
| Publicado en: | Schizophrenia Research Vol. 153; no. 1-3; pp. 109 - 113 |
|---|---|
| Autores principales: | , , , , |
| Formato: | research Journal Article |
| Publicado: |
Elsevier B.V.
Mar2014
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103813540&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103813540 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09209964 3PT jtl: Schizophrenia Research issn: 09209964 maglogo: N pubinfo: dt: Mar2014 vid: 153 iid: 1-3 pid: 1004 pub: Elsevier B.V. artinfo: ui: 103813540 NLM24548584 2012511821 10.1016/j.schres.2014.01.036 NLM24548584 103813540 ppf: 109 ppct: 4 formats: tig: atl: Brain functional connectivity during the experience of thought blocks in schizophrenic patients with persistent auditory verbal hallucinations: an EEG study. aug: au: Angelopoulos, Elias Koutsoukos, Elias Maillis, Antonis Papadimitriou, George N Stefanis, Costas affil: Signal Processing Laboratory, University Mental Health Research Institute, Athens, Greece; Department of Psychiatry, Eginition Hospital, Athens University Medical School, Athens, Greece. Electronic address: angelopoulos.ilias@gmail.com. sug: subj: Brain Physiology Brain Physiopathology Hallucinations Etiology Psychology Schizophrenia Complications Analysis of Variance Electroencephalography Female Human Male Neural Pathways Pathology Neural Pathways Physiopathology Psychological Tests Female Male ab: Thought blocks (TBs) are characterized by regular interruptions in the stream of thought. Outward signs are abrupt and repeated interruptions in the flow of conversation or actions while subjective experience is that of a total and uncontrollable emptying of the mind. In the very limited bibliography regarding TB, the phenomenon is thought to be conceptualized as a disturbance of consciousness that can be attributed to stoppages of continuous information processing due to an increase in the volume of information to be processed. In an attempt to investigate potential expression of the phenomenon on the functional properties of electroencephalographic (EEG) activity, an EEG study was contacted in schizophrenic patients with persisting auditory verbal hallucinations (AVHs) who additionally exhibited TBs. In this case, we hypothesized that the persistent and dense AVHs could serve the role of an increased information flow that the brain is unable to process, a condition that is perceived by the person as TB. Phase synchronization analyses performed on EEG segments during the experience of TBs showed that synchrony values exhibited a long-range common mode of coupling (grouped behavior) among the left temporal area and the remaining central and frontal brain areas. These common synchrony-fluctuation schemes were observed for 0.5 to 2s and were detected in a 4-s window following the estimated initiation of the phenomenon. The observation was frequency specific and detected in the broad alpha band region (6-12Hz). The introduction of synchrony entropy (SE) analysis applied on the cumulative synchrony distribution showed that TB states were characterized by an explicit preference of the system to be functioned at low values of synchrony, while the synchrony values are broadly distributed during the recovery state. Our results indicate that during TB states, the phase locking of several brain areas were converged uniformly in a narrow band of low synchrony values and in a distinct time window, impeding thus the ability of the system to recruit and to process information during this time window. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|