Pyoderma gangrenosum following breast reduction: treatment with topical tacrolimus and steroids.

Unlabelled: Pyoderma gangrenosum (PG) is a rare, noninfectious, inflammatory dermatosis usually associated with autoimmune disorders. Wounds may mimic a necrotizing infection, and the diagnosis is usually made after antibiotic therapy fails. Debridement may cause even larger wounds because of pather...

Descripción completa

Detalles Bibliográficos
Publicado en:Aesthetic Surgery Journal Vol. 34; no. 3; pp. 394 - 400
Autores principales: Doren, Erin Louise, Aya-Ay, Melanie Lynn
Formato: case study Journal Article
Publicado: Oxford University Press / USA Mar2014
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103814767&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 103814767
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        1090820X
        1XDY
      jtl: Aesthetic Surgery Journal
      issn: 1090820X
      maglogo: N
    pubinfo:
      dt: Mar2014
      vid: 34
      iid: 3
      pid: 622
      pub: Oxford University Press / USA
    artinfo:
      ui:
        103814767
        NLM24448967
        2012525758
        10.1177/1090820X13520448
        NLM24448967
        103814767
      ppf: 394
      ppct: 6
      formats:
      tig:
        atl: Pyoderma gangrenosum following breast reduction: treatment with topical tacrolimus and steroids.
      aug:
        au:
          Doren, Erin Louise
          Aya-Ay, Melanie Lynn
        affil: Dr Doren is an Integrated Plastic Surgery Resident in the Department of Surgery, Division of Plastic Surgery, University of South Florida, Tampa, Florida.
      sug:
        subj:
          Breast Diseases Etiology
          Immunosuppressive Agents Therapeutic Use
          Breast Reconstruction Adverse Effects
          Pyoderma Gangrenosum Etiology
          Breast Diseases Drug Therapy
          Breast Diseases Pathology
          Female
          Glucocorticoids Therapeutic Use
          Immunosuppressive Agents Administration and Dosage
          Middle Age
          Prednisone Therapeutic Use
          Pyoderma Gangrenosum Drug Therapy
          Pyoderma Gangrenosum Pathology
          Tacrolimus Administration and Dosage
          Tacrolimus Therapeutic Use
          Treatment Outcomes
          Middle Aged: 45-64 years
          Female
      ab: Unlabelled: Pyoderma gangrenosum (PG) is a rare, noninfectious, inflammatory dermatosis usually associated with autoimmune disorders. Wounds may mimic a necrotizing infection, and the diagnosis is usually made after antibiotic therapy fails. Debridement may cause even larger wounds because of pathergy, so PG treatment consists of corticosteroids and local wound care. Pyoderma gangrenosum can be a devastating complication of breast and aesthetic surgery. We describe a case of PG following unilateral breast reduction that resulted in systemic inflammatory response; after treatment with prednisone and topical tacrolimus, the PG was resolved. The application of topical tacrolimus may reduce the need for prolonged corticosteroids.Level Of Evidence: 5.
      pubtype: Academic Journal
      doctype:
        case study
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N