The movement of a nerve in a magnetic field: application to MRI Lorentz effect imaging.
Direct detection of neural activity with MRI would be a breakthrough innovation in brain imaging. A Lorentz force method has been proposed to image nerve activity using MRI; a force between the action currents and the static MRI magnetic field causes the nerve to move. In the presence of a magnetic...
| Publicado en: | Medical & Biological Engineering & Computing Vol. 52; no. 5; pp. 491 - 499 |
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| Autores principales: | , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
May2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103819141&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103819141 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: May2014 vid: 52 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 103819141 NLM24728667 2012554720 10.1007/s11517-014-1153-y NLM24728667 PMC4035360 103819141 ppf: 491 ppct: 8 formats: fmt: @attributes: type: P tig: atl: The movement of a nerve in a magnetic field: application to MRI Lorentz effect imaging. aug: au: Roth, Bradley J Luterek, Adam Puwal, Steffan affil: Department of Physics, Oakland University, Rochester, MI, 48309, USA, roth@oakland.edu. sug: subj: Action Potentials Physiology Nerve Fibers Physiology Electromagnetic Fields Magnetic Resonance Imaging Methods Models, Biological Electrophysiology ab: Direct detection of neural activity with MRI would be a breakthrough innovation in brain imaging. A Lorentz force method has been proposed to image nerve activity using MRI; a force between the action currents and the static MRI magnetic field causes the nerve to move. In the presence of a magnetic field gradient, this will cause the spins to precess at a different frequency, affecting the MRI signal. Previous mathematical modeling suggests that this effect is too small to explain the experimental data, but that model was limited because the action currents were assumed to be independent of position along the nerve and because the magnetic field was assumed to be perpendicular to the nerve. In this paper, we calculate the nerve displacement analytically without these two assumptions. Using realistic parameter values, the nerve motion is <5 nm, which induced a phase shift in the MRI signal of <0.02°. Therefore, our results suggest that Lorentz force imaging is beyond the capabilities of current technology. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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