Comparison between the M and XL probes for liver fibrosis assessment by transient elastography.
Objective: Liver stiffness measurement (LSM) using Transient Elastography (TE) for liver fibrosis assessment is difficult to be performed in obese and overweight patients by standard M probe, thus the XL probe was developed. The aim of our paper was to assess the usefulness of the XL probe in daily...
| Published in: | Medical Ultrasonography Vol. 16; no. 2; pp. 119 - 123 |
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| Main Authors: | , , , , , , , , |
| Format: | research Journal Article |
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Romanian Society of Ultrasonography in Medicine & Biology
Jun2014
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103821536&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103821536 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18444172 AX1S jtl: Medical Ultrasonography issn: 18444172 maglogo: N pubinfo: dt: Jun2014 vid: 16 iid: 2 pid: 57537 pub: Romanian Society of Ultrasonography in Medicine & Biology artinfo: ui: 103821536 103821536 NLM24791843 2012571700 NLM24791843 103821536 ppf: 119 ppct: 4 formats: fmt: @attributes: type: P tig: atl: Comparison between the M and XL probes for liver fibrosis assessment by transient elastography. aug: au: Sirli, Roxana Sporea, Ioan Deleanu, Alexandra Culcea, Laura Szilaski, Milana Popescu, Alina Danila, Mirela Şirli, Roxana Dănilă, Mirela affil: Department of Gastroenterology and Hepatology, "Victor Babes" University and Medicine Timisoara, Romania sug: subj: Ultrasonography Equipment and Supplies Liver Cirrhosis Ultrasonography Transducers Adult Aged Body Mass Index Equipment Design Female Hepatitis B, Chronic Ultrasonography Hepatitis C, Chronic Ultrasonography Human Liver Ultrasonography Male Middle Age Nonalcoholic Fatty Liver Disease Ultrasonography Obesity Ultrasonography Prospective Studies Reproducibility of Results Sensitivity and Specificity Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Objective: Liver stiffness measurement (LSM) using Transient Elastography (TE) for liver fibrosis assessment is difficult to be performed in obese and overweight patients by standard M probe, thus the XL probe was developed. The aim of our paper was to assess the usefulness of the XL probe in daily clinical practice.Material and Method: Our study included 216 patients (mean BMI 30.1+/-4.1 kg/m2) with chronic hepatopathies, in which paired measurements were made using the M (3.5MHz) and XL (2.5 MHz) probes in the same session. In each patient 10 valid LSM were acquired with each probe, a median was calculated, expressed in kiloPascals (kPa). Unreliable TE measurements were considered: fewer than 10 valid shots; with a success rate (SR) <60% and/or interquartile range interval (IQR) ≥30%.Results: In 127 patients reliable LSM could not be obtained by standard M probe, 10 of them normal weight, 25 of them overweight, and 92 obese. By XL probe reliable measurements were obtained in 80/127(63%) of these patients: 8/10 (80%) of the normal weights, 17/25 (68%) of the overweight and 55/92 (59.8%) of the obese. In 98 patients with reliable M probe measurements, XL probe LSMs were also performed. XL LS values strongly and significantly correlated with those obtained by M probe (Spearman r=0.789, p<0.0001), but were significantly lower [median 6.4 kPa (range 3.1 - 53.8) vs 7.7 kPa (range 3.7-69.1), Wilcoxon paired t test p<0.001)].Conclusion: By using the XL probe, reliable LSM by TE can be obtained in more than 60% of patients with unreliable measurements by M probe. LSM by XL probe are significantly correlated, but lower, than those obtained by M probe. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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