Emotional distress among adult survivors of childhood cancer.
Purpose: The purposes of this study were to estimate the prevalence of emotional distress in a large cohort of adult survivors of childhood cancer and to evaluate the interrelationship of risk factors including cancer-related late effects.Methods: Adult survivors of childhood cancer (N = 1,863), med...
| Publicado en: | Journal of Cancer Survivorship Vol. 8; no. 2; pp. 293 - 304 |
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| Autores principales: | , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jun2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103822132&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103822132 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19322259 46CU jtl: Journal of Cancer Survivorship issn: 19322259 maglogo: N pubinfo: dt: Jun2014 vid: 8 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 103822132 NLM24459073 2012574761 10.1007/s11764-013-0336-0 NLM24459073 PMC4098755 103822132 ppf: 293 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Emotional distress among adult survivors of childhood cancer. aug: au: Oancea, S Cristina Brinkman, Tara M Ness, Kirsten K Krull, Kevin R Smith, Webb A Srivastava, D Kumar Robison, Leslie L Hudson, Melissa M Gurney, James G affil: Master of Public Health Program, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, USA. sug: subj: Neoplasms Mortality Neoplasms Psychosocial Factors Stress, Psychological Epidemiology Survivors Adult Brief Symptom Inventory Clinical Assessment Tools Female Human Male Multivariate Analysis Neoplasms Physiopathology Pain Psychosocial Factors Prevalence Funding Source Adult: 19-44 years Female Male ab: Purpose: The purposes of this study were to estimate the prevalence of emotional distress in a large cohort of adult survivors of childhood cancer and to evaluate the interrelationship of risk factors including cancer-related late effects.Methods: Adult survivors of childhood cancer (N = 1,863), median age of 32 years at follow-up, completed comprehensive medical evaluations. Clinically relevant emotional distress was assessed using the Brief Symptom Inventory 18 and was defined as T-scores ≥63. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using multivariable logistic regression models to identify risk factors for distress. Path analysis was used to examine associations among identified risk factors.Results: Elevated global distress was reported by 15.1% of survivors. Cancer-related pain was associated with elevated distress (OR 8.72; 95% CI, 5.32-14.31). Survivors who reported moderate learning or memory problems were more likely to have elevated distress than survivors who reported no learning or memory problems (OR 3.27; 95% CI, 2.17-4.93). Path analysis implied that cancer-related pain has a direct effect on distress symptoms and an indirect effect through socioeconomic status and learning or memory problems. Similar results were observed for learning or memory problems.Conclusions: Childhood cancer-related morbidities including pain and learning or memory problems appear to be directly and indirectly associated with elevated distress symptoms decades after treatment. Understanding these associations may help inform intervention targets for survivors of childhood cancer experiencing symptoms of distress.Implications For Cancer Survivors: A subset of long-term childhood cancer survivors experience significant emotional distress. Physical and cognitive late effects may contribute to these symptoms. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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