Volumetric evaluation of hepatic tumors: multi-vendor, multi-reader liver phantom study.

Purpose: To compare liver lesion volume measurement on multiple 3D software platforms using a liver phantom. Methods: An anthropomorphic phantom constructed with ten liver lesions of varying size, attenuation, and shape with known volume and long axis measurement was scanned (120 kVp, 80-440 smart m...

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Publicado en:Abdominal Imaging Vol. 39; no. 3; pp. 488 - 497
Autores principales: Lubner, Meghan G, Dustin Pooler, B, Del Rio, Alejandro Munoz, Durkee, Ben, Pickhardt, Perry J
Formato: research Journal Article
Publicado: Springer Nature Jun2014
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2014
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      pub: Springer Nature
      place: New York, New York
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        atl: Volumetric evaluation of hepatic tumors: multi-vendor, multi-reader liver phantom study.
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          Lubner, Meghan G
          Dustin Pooler, B
          Del Rio, Alejandro Munoz
          Durkee, Ben
          Pickhardt, Perry J
        affil: Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3/311 Clinical Science Center, 600 Highland Ave., Madison, WI, 53792-3252, USA, mlubner@uwhealth.org.
      sug:
        subj:
          Imaging, Three-Dimensional Methods
          Liver Neoplasms Pathology
          Liver Neoplasms Radiography
          Radiographic Image Interpretation, Computer-Assisted Methods
          Tomography, X-Ray Computed Methods
          Body Weights and Measures
          Human
          Liver Radiography
          Observer Bias
          Phantoms, Imaging
          Reproducibility of Results
          Software
      ab: Purpose: To compare liver lesion volume measurement on multiple 3D software platforms using a liver phantom. Methods: An anthropomorphic phantom constructed with ten liver lesions of varying size, attenuation, and shape with known volume and long axis measurement was scanned (120 kVp, 80-440 smart mA, NI 12). DICOM data were uploaded to five commercially available 3D visualization systems and manual tumor volume was obtained by three-independent readers. Accuracy and reproducibility of linear and volume measurements were compared. The two most promising systems were then compared with an additional prototype system by two readers using both manual and semi-automated measurement with similar comparison between linear and volume measures. Measurements were performed on 5- and 1.25-mm data sets. Inter- and intra-observer variability was also assessed. Results: Overall mean % volume error on the five commercially available software systems (averaging all ten liver lesions among all three readers) was 8.0% ± 7.5%, 13.7% ± 11.2%, 14.2% ± 15.2%, 16.4% ± 14.8 %, and 16.9% ± 13.8%, varying almost twofold across vendor. Moderate inter-observer variability was present. Volume measurement was slightly more accurate than linear measurement, but linear measurement was more reproducible across readers and systems. On the two "best" systems, the manual measurement method was more accurate than the automated method (p = 0.001). The prototype system demonstrated superior semi-automated assessment, with a mean % volume error of 5.3% ± 4.1% (vs. 17.8% ± 11.1% and 31.5% ± 19.7%, p < 0.001), with improved inter- and intra-observer variability. Conclusions: Accuracy and reproducibility of volume assessment of liver lesions varies significantly by vendor, which has important implications for clinical use.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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