Potential biases in the classification, analysis and interpretations in cross-sectional study: commentaries - surrounding the article "resting heart rate: its correlations and potential for screening metabolic dysfunctions in adolescents".
Background: Resting heart rate reflects sympathetic nerve activity. A significant association between resting heart rate (HR) and all causes of cardiovascular mortality has been reported by some epidemiologic studies. Despite suggestive evidence, resting heart rate (RHR) has not been formally explor...
| Publicado en: | BMC Pediatrics Vol. 14; no. 1; pp. 117 - 118 |
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| Autores principales: | , , , |
| Formato: | commentary Journal Article |
| Publicado: |
BioMed Central
2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103826840&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103826840 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14712431 1CIE jtl: BMC Pediatrics issn: 14712431 maglogo: N pubinfo: dt: 2014 vid: 14 iid: 1 pid: 24147 pub: BioMed Central artinfo: ui: 103826840 103826840 NLM24885992 2012605944 10.1186/1471-2431-14-117 NLM24885992 PMC4012522 103826840 ppf: 117 ppct: 1 formats: tig: atl: Potential biases in the classification, analysis and interpretations in cross-sectional study: commentaries - surrounding the article "resting heart rate: its correlations and potential for screening metabolic dysfunctions in adolescents". aug: au: de Moraes, Augusto César Ferreira Cassenote, Alex Jones Flores Moreno, Luis A Carvalho, Heráclito Barbosa affil: Department of Preventive Medicine, School of Medicine of the University of Sao Paulo, Sao Paulo, SP, Brazil. moraes82@yahoo.com.br. sug: subj: Blood Glucose Metabolism Hyperlipidemia Physiopathology Heart Rate Physiology Hyperglycemia Physiopathology Health Screening Methods Relaxation Physiology Female Male Female Male ab: Background: Resting heart rate reflects sympathetic nerve activity. A significant association between resting heart rate (HR) and all causes of cardiovascular mortality has been reported by some epidemiologic studies. Despite suggestive evidence, resting heart rate (RHR) has not been formally explored as a prognostic factor and potential therapeutic outcome and, therefore, is not generally accepted in adolescents.Discussion: The core of the debate is the methodological aspects used in "Resting heart rate: its correlations and potential for screening metabolic dysfunctions in adolescents"; the points are: cutoff used for cluster RHR, two different statistical models used to analyze the same set of variables, one for continuous data, and another for categorical data; interpretation of p-value < 0.05, sampling process involving two random stages, analysis of design effect and the parameters of screening tests.Summary: Aspects that must be taken into account for evaluation of a screening test to measure the potential for discrimination for a common variable (population with outcome vs. no outcome population), the main indicators are: sensitivity, specificity, accuracy, positive predictive value and negative predictive value. The measures of argumentation equality (CI) or difference (p-valor) are important to validate these indicators but do not indicate quality of screening. pubtype: Academic Journal doctype: commentary Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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