Automatic segmentation of the aortic root in CT angiography of candidate patients for transcatheter aortic valve implantation.

Transcatheter aortic valve implantation is a minimal-invasive intervention for implanting prosthetic valves in patients with aortic stenosis. Accurate automated sizing for planning and patient selection is expected to reduce adverse effects such as paravalvular leakage and stroke. Segmentation of th...

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Publicado en:Medical & Biological Engineering & Computing Vol. 52; no. 7; pp. 611 - 619
Autores principales: Elattar, M A, Wiegerinck, E M, Planken, R N, Vanbavel, E, van Assen, H C, Baan Jr, J, Marquering, H A, Baan, J Jr
Formato: research Journal Article
Publicado: Springer Nature Jul2014
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2014
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      pub: Springer Nature
      place: New York, New York
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        atl: Automatic segmentation of the aortic root in CT angiography of candidate patients for transcatheter aortic valve implantation.
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          Elattar, M A
          Wiegerinck, E M
          Planken, R N
          Vanbavel, E
          van Assen, H C
          Baan Jr, J
          Marquering, H A
          Baan, J Jr
        affil: Department of Biomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands, mustafa.elattar@gmail.com.
      sug:
        subj:
          Angiography Methods
          Aortic Valve Radiography
          Image Processing, Computer Assisted Methods
          Tomography, X-Ray Computed Methods
          Heart Valve Prosthesis Methods
          Algorithms
          Human
          Reproducibility of Results
      ab: Transcatheter aortic valve implantation is a minimal-invasive intervention for implanting prosthetic valves in patients with aortic stenosis. Accurate automated sizing for planning and patient selection is expected to reduce adverse effects such as paravalvular leakage and stroke. Segmentation of the aortic root in CTA is pivotal to enable automated sizing and planning. We present a fully automated segmentation algorithm to extract the aortic root from CTA volumes consisting of a number of steps: first, the volume of interest is automatically detected, and the centerline through the ascending aorta and aortic root centerline are determined. Subsequently, high intensities due to calcifications are masked. Next, the aortic root is represented in cylindrical coordinates. Finally, the aortic root is segmented using 3D normalized cuts. The method was validated against manual delineations by calculating Dice coefficients and average distance error in 20 patients. The method successfully segmented the aortic root in all 20 cases. The mean Dice coefficient was 0.95 ± 0.03, and the mean radial absolute error was 0.74 ± 0.39 mm, where the interobserver Dice coefficient was 0.95 ± 0.03 and the mean error was 0.68 ± 0.34 mm. The proposed algorithm showed accurate results compared to manual segmentations.
      pubtype: Academic Journal
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        Journal Article
      ougenre: Article
    language: English
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