Obesity and depression in adolescence and beyond: reciprocal risks.

Objective: Obesity and major depressive disorder (MDD) are associated, but evidence about how they relate over time is conflicting. The goal of this study was to examine prospective associations between depression and obesity from early adolescence through early adulthood.Methods: Participants were...

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Published in:International Journal of Obesity Vol. 38; no. 7; pp. 906 - 912
Main Authors: Marmorstein, N R, Iacono, W G, Legrand, L
Format: research Journal Article
Published: Springer Nature Jul2014
Online Access:View this record in EBSCOhost
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        03070565
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      jtl: International Journal of Obesity
      issn: 03070565
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      dt: Jul2014
      vid: 38
      iid: 7
      pid: 2579
      pub: Springer Nature
      place: Dordrecht, <Blank>
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        103832810
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        2012642013
        10.1038/ijo.2014.19
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        103832810
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        atl: Obesity and depression in adolescence and beyond: reciprocal risks.
      aug:
        au:
          Marmorstein, N R
          Iacono, W G
          Legrand, L
        affil: Department of Psychology, Rutgers University, Camden, NJ, USA.
      sug:
        subj:
          Adolescent Behavior
          Antidepressive Agents Therapeutic Use
          Depression Prevention and Control
          Obesity Prevention and Control
          Adolescence
          Adult
          Age of Onset
          Cross Sectional Studies
          Depression Epidemiology
          Depression Psychosocial Factors
          Female
          Human
          Male
          Minnesota
          Obesity Epidemiology
          Obesity Psychosocial Factors
          Odds Ratio
          Prospective Studies
          Risk Assessment
          Severity of Illness Indices
          Sex Factors
          Adolescent: 13-18 years
          Adult: 19-44 years
          Female
          Male
      ab: Objective: Obesity and major depressive disorder (MDD) are associated, but evidence about how they relate over time is conflicting. The goal of this study was to examine prospective associations between depression and obesity from early adolescence through early adulthood.Methods: Participants were drawn from a statewide, community-based, Minnesota sample. MDD and obesity with onsets by early adolescence (by age 14), late adolescence (between 14 and 20) and early adulthood (ages 20-24) were assessed via structured interview (depression) and study-measured height and weight.Results: Cross-sectional results indicated that depression and obesity with onsets by early adolescence were concurrently associated, but the same was not true later in development. Prospective results indicated that depression by early adolescence predicted the onset of obesity (odds ratio (OR)=3.76, confidence interval =1.33-10.59) during late adolescence among female individuals. Obesity that developed during late adolescence predicted the onset of depression (OR=5.89, confidence interval=2.31-15.01) during early adulthood among female individuals.Conclusions: For girls, adolescence is a high-risk period for the development of this comorbidity, with the nature of the risk varying over the course of adolescence. Early adolescent-onset depression is associated with elevated risk of later onset obesity, and obesity, particularly in late adolescence, is associated with increased odds of later depression. Further investigation into the mechanisms of these effects and the reasons for the observed gender and developmental differences is needed. Prevention programs focused on early-onset cases of depression and adolescent-onset cases of obesity, particularly among female individuals, may help in reducing risk for this form of comorbidity.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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