Recurrent pyoderma gangrenosum precipitated by breast cancer: a case report and review of the literature.
Introduction: Pyoderma gangrenosum is a rare clinical entity of poorly understood pathogenesis, characterized by rapidly progressing skin necrosis. In around half of patients pyoderma gangrenosum is a manifestation of underlying systemic diseases, such as rheumatoid arthritis, inflammatory bowel dis...
| Publicado en: | Journal of Medical Case Reports Vol. 8; no. 1; pp. 226 - 227 |
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| Autores principales: | , , , , |
| Formato: | case study review Journal Article |
| Publicado: |
BioMed Central
2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103833347&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103833347 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 17521947 8X8Q jtl: Journal of Medical Case Reports issn: 17521947 maglogo: N pubinfo: dt: 2014 vid: 8 iid: 1 pid: 24147 pub: BioMed Central artinfo: ui: 103833347 103833347 NLM24965126 2012643986 10.1186/1752-1947-8-226 NLM24965126 PMC4090656 103833347 ppf: 226 ppct: 1 formats: tig: atl: Recurrent pyoderma gangrenosum precipitated by breast cancer: a case report and review of the literature. aug: au: Duchnowska, Renata Ziajka, Ewa Góralska, Agnieszka Grala, Bartlomiej Grala, Bartłomiej affil: Department of Oncology, Military Institute of Medicine, Szaserów 128 Street, 04-141 Warsaw, Poland. rdtt@wp.pl. sug: subj: Breast Neoplasms Complications Carcinoma, Ductal, Breast Complications Leg Ulcer Etiology Pyoderma Gangrenosum Etiology Aged Female Recurrence Aged: 65+ years Female ab: Introduction: Pyoderma gangrenosum is a rare clinical entity of poorly understood pathogenesis, characterized by rapidly progressing skin necrosis. In around half of patients pyoderma gangrenosum is a manifestation of underlying systemic diseases, such as rheumatoid arthritis, inflammatory bowel disease or myeloproliferative disorders. There have been very few reports on the association of pyoderma gangrenosum with solid malignancies.Case Presentation: We report a case of a 68-year-old Caucasian woman in whom pyoderma gangrenosum first appeared around 30 years earlier, at the time of exacerbation of rheumatoid arthritis, and recurred as a manifestation of locally advanced breast cancer. The causative role of the neoplastic process was partly confirmed by the healing of the skin ulceration only following effective endocrine cancer therapy, whereas earlier attempts with standard anti-inflammatory therapy were unsuccessful.Conclusions: Pyoderma gangrenosum has a recurrent nature and may be reactivated by various causes within several years. Therefore, a prompt and thorough diagnosis accompanied by treatment of the underlying disease is necessary. pubtype: Academic Journal doctype: case study review Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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