Real time sonoelastographic evaluation of renal allografts in correlation with clinical prognostic parameters: comparison of linear and convex transducers according to segmental anatomy.
Background: Renal transplantation is the treatment of choice in end-stage renal disease. Chronic allograft dysfunction is the leading cause of chronic allograft failure. Surveillance biopsy is the only reliable tool to detect early fibrosis in the allograft. There is a need for non-invasive methods...
| Publicado en: | Medical Ultrasonography Vol. 16; no. 3; pp. 229 - 236 |
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| Autores principales: | , , , , , |
| Formato: | research Journal Article |
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Romanian Society of Ultrasonography in Medicine & Biology
Sep2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103839549&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103839549 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18444172 AX1S jtl: Medical Ultrasonography issn: 18444172 maglogo: N pubinfo: dt: Sep2014 vid: 16 iid: 3 pid: 57537 pub: Romanian Society of Ultrasonography in Medicine & Biology artinfo: ui: 103839549 NLM25110764 2012682290 10.11152/mu.2013.2066.163.igt1 NLM25110764 103839549 ppf: 229 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Real time sonoelastographic evaluation of renal allografts in correlation with clinical prognostic parameters: comparison of linear and convex transducers according to segmental anatomy. aug: au: Tatar, Idil Gunes Teber, Mehmet Akif Ogur, Torel Kurt, Aydin Hekimoglu, Baki Kurt, Aydın affil: Diskapi Training and Research Hospital, Department Of Radiology, Ankara, Turkey sug: subj: Ultrasonography Equipment and Supplies Kidney Pathology Kidney Ultrasonography Kidney Transplantation Postoperative Complications Ultrasonography Adult Aged Computer Systems Equipment Design Female Fibrosis Ultrasonography Human Male Middle Age Prognosis Young Adult Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Background: Renal transplantation is the treatment of choice in end-stage renal disease. Chronic allograft dysfunction is the leading cause of chronic allograft failure. Surveillance biopsy is the only reliable tool to detect early fibrosis in the allograft. There is a need for non-invasive methods for the detection of early development of renal allograft fibrosis.Aims: To analyze the reliability of sonographic elasticity index and resistive index measurements in the evaluation of renal transplant fibrosis using linear and convex transducers according to segmental anatomy.Materials and Methods: Elasticity index and resistive index were measured in 28 renal transplants and correlated with clinical prognostic parameters. Donor age above 50 years old, post transplantation time over 60 months and serum creatinine level above 1.5 mg/dl were defined as poor prognostic parameters.Results: Renal transplant recipients with serum creatinine level above 1.5 mg/dl demonstrated higher mean elasticity index (p=0.006) with a convex probe and higher elasticity index in the middle segments both with a convex and a matrix linear probe (p=0.026, p=0.001). Renal transplant recipients with post-transplantation time of 60 months and more demonstrated higher resistive index values in the middle segments (p=0.016).Conclusions: Convex probe was able to detect the changes in mean stiffness better than the matrix linear probe. The measurements from subsegments might suggest that diffuse changes in stiffness can truly be detected in the middle segments or that fibrotic processes start from the middle segments of the renal transplants. Further studies correlated with histopathology are required to validate the findings. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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