Chinese herbal medicines in the treatment of IBD and colorectal cancer: a review.

Opinion Statement: Inflammatory bowel diseases (IBD) are a group of chronic inflammatory gastrointestinal (GI) disorders, mainly represented by Crohn's disease and ulcerative colitis. Although the etiology of IBD is not fully understood, there is substantial evidence that immunologic, genetic, and e...

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Publicado en:Current Treatment Options in Oncology Vol. 15; no. 3; pp. 405 - 421
Autores principales: Salaga, Maciej, Zatorski, Hubert, Sobczak, Marta, Chen, Chunqiu, Fichna, Jakub, Sałaga, Maciej
Formato: meta analysis research systematic review Journal Article
Publicado: Springer Nature Sep2014
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: Chinese herbal medicines in the treatment of IBD and colorectal cancer: a review.
      aug:
        au:
          Salaga, Maciej
          Zatorski, Hubert
          Sobczak, Marta
          Chen, Chunqiu
          Fichna, Jakub
          Sałaga, Maciej
        affil: Department of Biochemistry, Faculty of Medicine, Medical University of Lodz, Mazowiecka 6/8, 92-215, Lodz, Poland
      sug:
        subj:
          Colorectal Neoplasms Drug Therapy
          Drugs, Chinese Herbal Therapeutic Use
          Inflammatory Bowel Diseases Drug Therapy
          Medicine, Chinese Traditional
          Animals
          Clinical Trials
          Drug Evaluation, Preclinical
          Human
          Meta Analysis
          Models, Biological
          Professional Practice, Evidence-Based
          Systematic Review
      ab: Opinion Statement: Inflammatory bowel diseases (IBD) are a group of chronic inflammatory gastrointestinal (GI) disorders, mainly represented by Crohn's disease and ulcerative colitis. Although the etiology of IBD is not fully understood, there is substantial evidence that immunologic, genetic, and environmental factors are the main contributors in IBD pathogenesis. Conventional therapies for IBD include anti-inflammatory and immunosuppressive drugs, such as 5-aminosalicylic acid, corticosteroids, antibiotics, and biologicals, such as anti-TNFα antibodies. However, because of low efficacy and high risk of side effects, there is a clear need for the development of novel and efficient pharmacologic strategies in IBD treatment. Among various complementary and alternative medicine (CAM) approaches, which are used for the treatment of gastrointestinal (GI) disorders, traditional Chinese medicine (TCM) is one of the most developed and diversified. TCM encompasses methods and therapies that emerged over centuries and is based mostly on ethnic wisdom and observations transmitted from generation to generation. In the recent years, the efficacy of TCM as treatment of IBD has been extensively characterized in preclinical and clinical studies, which resulted in a significant number of research reports. Moreover, the popularity of TCM among patients with IBD has rapidly increased not only in Asia, but also in the Western hemisphere.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        Journal Article
      ougenre: Article
    language: English
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