Decreased photoreceptor inner segment/outer segment junction reflectivity in patients with idiopathic epimacular membrane.
Purpose: To assess the effects of idiopathic epimacular membrane (IEMM) on retinal pigment epithelium (RPE), photoreceptor inner segment/outer segment (IS/OS) junction, and external limiting membrane (ELM) reflectivities to determine functional alterations in these layers using optical coherence tom...
| Publicado en: | Eye (0950-222X) Vol. 28; no. 9; pp. 1126 - 1131 |
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| Autores principales: | , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Sep2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103845495&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103845495 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0950222X LK5 jtl: Eye (0950-222X) issn: 0950222X maglogo: Y pubinfo: dt: Sep2014 vid: 28 iid: 9 pid: 2579 pub: Springer Nature place: Dordrecht, <Blank> artinfo: ui: 103845495 NLM24993328 2012726904 10.1038/eye.2014.147 NLM24993328 PMC4166636 103845495 ppf: 1126 ppct: 5 formats: tig: atl: Decreased photoreceptor inner segment/outer segment junction reflectivity in patients with idiopathic epimacular membrane. aug: au: Toprak, I Yaylali, V Yildirim, C Yaylalı, V affil: Department of Ophthalmology, Faculty of Medicine, Pamukkale University, Denizli, Turkey sug: subj: Retinal Diseases Diagnosis Photoreceptors Pathology Aged Basement Membrane Pathology Female Human Male Middle Age Retrospective Design Tomography, Optical Coherence Visual Acuity Physiology Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Purpose: To assess the effects of idiopathic epimacular membrane (IEMM) on retinal pigment epithelium (RPE), photoreceptor inner segment/outer segment (IS/OS) junction, and external limiting membrane (ELM) reflectivities to determine functional alterations in these layers using optical coherence tomography (OCT) image analysis.Methods: Fifty eyes of 50 patients with untreated IEMM and 41 eyes of 41 age- and sex-matched healthy controls with normal OCT scans were retrospectively reviewed. A single masked physician analyzed OCT images randomly. Reflectivity values of RPE, IS/OS junction, and ELM were obtained using 'plot profile' mode of a medical image processing computer software.Results: The study comprised 50 patients with untreated IEMM and age- and sex-matched 41 control subjects (P > 0.05). Image analysis demonstrated that IS/OS junction and ELM had significantly lower reflectivity in patients with IEMM compared with those of the control eyes (P = 0.008, P = 0.009, respectively). However, RPE reflectivity did not differ between two groups (P = 0.100). Correlation analyses showed no significant associations between reflectivity values and corrected visual acuity (P > 0.05).Conclusion: In patients with IEMM, photoreceptor IS/OS junction and ELM seem to have lower reflectivity, which might indicate impaired functionality even though these layers are not apparently damaged on OCT imaging. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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