Language changes coincide with motor and fMRI changes following upper extremity motor therapy for hemiparesis: a brief report.
To formally assess changes in language, affected UE movement, and motor functional activation changes via functional magnetic resonance imaging (fMRI) following participation in motor therapy without any accompanying language intervention. Pre-post case series. Five subjects with stroke exhibiting c...
| Publicado en: | Brain Imaging & Behavior Vol. 8; no. 3; pp. 370 - 378 |
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| Autores principales: | , , , , |
| Formato: | research randomized controlled trial Journal Article |
| Publicado: |
Springer Nature
Sep2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103847060&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103847060 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19317557 3GSC jtl: Brain Imaging & Behavior issn: 19317557 maglogo: N pubinfo: dt: Sep2014 vid: 8 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 103847060 NLM21989635 2012741174 10.1007/s11682-011-9139-y NLM21989635 103847060 ppf: 370 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Language changes coincide with motor and fMRI changes following upper extremity motor therapy for hemiparesis: a brief report. aug: au: Harnish, Stacy Meinzer, Marcus Trinastic, Jonathan Fitzgerald, David Page, Stephen affil: , Columbus, OH, USA. sug: subj: Brain Physiopathology Hemiplegia Physiopathology Hemiplegia Rehabilitation Language Motor Activity Physiology Upper Extremity Physiopathology Aged Cerebrovascular Circulation Physiology Chronic Disease Clinical Assessment Tools Dominance, Cerebral Electrotherapy Methods Hemiplegia Etiology Human Language Tests Magnetic Resonance Imaging Manual Therapy Methods Middle Age Oxygen Blood Severity of Illness Indices Stroke Complications Stroke Physiopathology Stroke Rehabilitation Treatment Outcomes Aged: 65+ years Middle Aged: 45-64 years ab: To formally assess changes in language, affected UE movement, and motor functional activation changes via functional magnetic resonance imaging (fMRI) following participation in motor therapy without any accompanying language intervention. Pre-post case series. Five subjects with stroke exhibiting chronic, stable UE hemiparesis. The upper extremity section of the Fugl-Meyer (FM), the Western Aphasia Battery (WAB), and functional magnetic resonance imaging (fMRI), administered during performance of an affected UE motor task. All subjects were administered six weeks of repetitive task specific training (RTP), performed for approximately 2.5 hours per day, split into two sessions. For the first four weeks of the intervention period, RTP was administered every weekday, whereas, for the subsequent two weeks, RTP was administered 3 days/week. Epidural cortical stimulation was co-administered with the RTP via an electrode array and implanted pulse generator. For all sessions, one subject worked with a single therapist. Four weeks before and four weeks after the intervention period, all subjects were administered the FM, WAB, and fMRI. Three of the subjects exhibited clinically significant language changes on the WAB. These individuals exhibited the largest motor changes as measured by the FM. Functional MRI revealed distinct motor activation patterns in these subjects, characterized by more strongly right lateralized focal BOLD activity or a shift in activation toward the right hemisphere. Language changes appear to co-occur with motor changes after UE RTP. Understanding the underlying mechanisms of these findings may lead to more efficient and synergistic rehabilitative therapy delivery. pubtype: Academic Journal doctype: research randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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