Feature selection and classification of leukocytes using random forest.

In automatic segmentation of leukocytes from the complex morphological background of tissue section images, a vast number of artifacts/noise are also extracted causing large amount of multivariate data generation. This multivariate data degrades the performance of a classifier to discriminate betwee...

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Publicado en:Medical & Biological Engineering & Computing Vol. 52; no. 12; pp. 1041 - 1053
Autores principales: Saraswat, Mukesh, Arya, K V
Formato: research Journal Article
Publicado: Springer Nature Dec2014
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2014
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      pub: Springer Nature
      place: New York, New York
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        atl: Feature selection and classification of leukocytes using random forest.
      aug:
        au:
          Saraswat, Mukesh
          Arya, K V
        affil: ABV-Indian Institute of Information Technology and Management, Gwalior, 474010, India, saraswatmukesh@gmail.com.
      sug:
        subj:
          Decision Trees
          Image Processing, Computer Assisted Methods
          Information Science Methods
          Leukocytes
          Leukocytes Classification
          Algorithms
          Animal Studies
          Mice
          Models, Biological
          Skin
      ab: In automatic segmentation of leukocytes from the complex morphological background of tissue section images, a vast number of artifacts/noise are also extracted causing large amount of multivariate data generation. This multivariate data degrades the performance of a classifier to discriminate between leukocytes and artifacts/noise. However, the selection of prominent features plays an important role in reducing the computational complexity and increasing the performance of the classifier as compared to a high-dimensional features space. Therefore, this paper introduces a novel Gini importance-based binary random forest feature selection method. Moreover, the random forest classifier is used to classify the extracted objects into artifacts, mononuclear cells, and polymorphonuclear cells. The experimental results establish that the proposed method effectively eliminates the irrelevant features, maintaining the high classification accuracy as compared to other feature reduction methods.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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