The suitability of EBC-Pb as a new biomarker to assess occupational exposure to lead...exhaled breath condensate
Occupational exposure to lead (Pb) requires continuous surveillance to assure, as much as possible, safe and healthful working conditions. This study addresses the suitability of assessing Pb exposure in relevant workers using their exhaled breath condensate (EBC). This study enrolled workers of two...
| Publicado en: | International Journal of Environmental Health Research Vol. 25; no. 1; pp. 67 - 81 |
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| Autores principales: | , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Feb2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103860848&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103860848 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09603123 57L jtl: International Journal of Environmental Health Research issn: 09603123 maglogo: Y pubinfo: dt: Feb2015 vid: 25 iid: 1 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 103860848 100014943 10.1080/09603123.2014.893569 NLM24670229 103860848 ppf: 67 ppct: 14 formats: fmt: @attributes: type: P tig: atl: The suitability of EBC-Pb as a new biomarker to assess occupational exposure to lead...exhaled breath condensate aug: au: Félix, Pedro M. Almeida, Susana Marta Franco, Cristiana Almeida, António Bugalho Lopes, Carlos Claro, Maria Inês Fragoso, Elsa Teles, Catarina Wolterbeek, Hubert Th. Pinheiro, Teresa affil: Campus Tecnológico e Nuclear, Dpt Física, Instituto Superior Técnico, Universidade Técnica de Lisboa, Lisboa, Portugal sug: subj: Occupational Exposure Lead Adverse Effects Lead Blood Biological Markers Breath Tests Human Work Environment Descriptive Statistics Questionnaires Particulate Matter Spirometry Respiratory Function Tests Data Analysis Software Mann-Whitney U Test Post Hoc Analysis Chi Square Test Male Female Adult Middle Age Funding Source European Union Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Occupational exposure to lead (Pb) requires continuous surveillance to assure, as much as possible, safe and healthful working conditions. This study addresses the suitability of assessing Pb exposure in relevant workers using their exhaled breath condensate (EBC). This study enrolled workers of two different Pb processing industries characterized by moderate and high Pb exposure levels in the work environment, and a group of non-exposed individuals working in offices who served as baseline for Pb exposure. The EBC-Pb of workers reflected the Pb levels in the work environment of all three settings, although the relationship with B-Pb was not clear. The lack of correlation between EBC-Pb and B-Pb most probably indicates the time lag for Pb to enter in the two body pools. The EBC-Pb seems to reflect immediate exposure, providing a prompt signature of Pb in the environmental that may interact directly with the organ. By delivering short-term evaluation of exposure, EBC-Pb represents a clear advantage in biomonitoring and may become an interesting tool for estimating organ burden. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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