Accuracy and validation of an automated electronic algorithm to identify patients with atrial fibrillation at risk for stroke.

Background: There is no universally accepted algorithm for identifying atrial fibrillation (AF) patients and stroke risk using electronic data for use in performance measures.Methods: Patients with AF seen in clinic were identified based on International Classification of Diseases, Ninth Revision(IC...

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Publicado en:American Heart Journal Vol. 169; no. 1; pp. 39 - 40
Autores principales: Navar-Boggan, Ann Marie, Rymer, Jennifer A, Piccini, Jonathan P, Shatila, Wassim, Ring, Lauren, Stafford, Judith A, Al-Khatib, Sana M, Peterson, Eric D
Formato: research Journal Article
Publicado: Elsevier B.V. Jan2015
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Elsevier B.V.
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        atl: Accuracy and validation of an automated electronic algorithm to identify patients with atrial fibrillation at risk for stroke.
      aug:
        au:
          Navar-Boggan, Ann Marie
          Rymer, Jennifer A
          Piccini, Jonathan P
          Shatila, Wassim
          Ring, Lauren
          Stafford, Judith A
          Al-Khatib, Sana M
          Peterson, Eric D
        affil: Duke University Medical Center, Durham, NC. Electronic address: ann.navar@duke.edu.
      sug:
        subj:
          Algorithms
          Atrial Fibrillation Epidemiology
          Stroke Epidemiology
          Aged
          Aged, 80 and Over
          Anticoagulants Therapeutic Use
          Atrial Fibrillation Drug Therapy
          Female
          Human
          Male
          Middle Age
          Risk Assessment Methods
          Sensitivity and Specificity
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: Background: There is no universally accepted algorithm for identifying atrial fibrillation (AF) patients and stroke risk using electronic data for use in performance measures.Methods: Patients with AF seen in clinic were identified based on International Classification of Diseases, Ninth Revision(ICD-9) codes. CHADS(2) and CHA(2)DS(s)-Vasc scores were derived from a broad, 10-year algorithm using IICD-9 codes dating back 10 years and a restrictive, 1-year algorithm that required a diagnosis within the past year. Accuracy of claims-based AF diagnoses and of each stroke risk classification algorithm were evaluated using chart reviews for 300 patients. These algorithms were applied to assess system-wide anticoagulation rates.Results: Between 6/1/2011, and 5/31/2012, we identified 6,397 patients with AF. Chart reviews confirmed AF or atrial flutter in 95.7%. A 1-year algorithm using CHA(2)DS(2)-Vasc score ≥2 to identify patients at risk for stroke maximized positive predictive value (97.5% [negative predictive value 65.1%]). The PPV of the 10-year algorithm using CHADS(2) was 88.0%; 12% those identified as high-risk had CHADS(2) scores <2. Anticoagulation rates were identical using 1-year and 10-year algorithms for patients with CHADS(2) scores ≥2 (58.5% on anticoagulation) and CHA(2)DS(2)-Vasc scores ≥2 (56.0% on anticoagulation).Conclusions: Automated methods can be used to identify patients with prevalent AF indicated for anticoagulation but may have misclassification up to 12%, which limits the utility of relying on administrative data alone for quality assessment. Misclassification is minimized by requiring comorbidity diagnoses within the prior year and using a CHA(2)DS(2)-Vasc based algorithm. Despite differences in accuracy between algorithms, system-wide anticoagulation rates assessed were similar regardless of algorithm used.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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