Role of Intraoperative Pathology Consultation in Skeletal Tumors and Tumor-Like Lesions.
Early and accurate detection of bone tumors and their staging are important since some of them are highly malignant. Intraoperative pathological consultation in bone tumors and tumor-like conditions is quite complex; however, it allows improvement in prognosis and limb salvage. Present study was con...
| Publicado en: | Sarcoma pp. 1 - 7 |
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| Autores principales: | , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103868929&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103868929 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 1357714X 57R jtl: Sarcoma issn: 1357714X maglogo: Y pubinfo: dt: 2014 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 103868929 103868929 2012851266 NLM24955018 PMC4052531 103868929 ppf: 1 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Role of Intraoperative Pathology Consultation in Skeletal Tumors and Tumor-Like Lesions. aug: au: Bhaker, Poonam Mohan, Harsh Handa, Uma Kumar, Sudhir affil: Department of Pathology, Research Block-A, Post Graduate Institute of Medical Education and Research, Sector-12, Chandigarh 160012, India sug: subj: Intraoperative Period Referral and Consultation Bone Neoplasms Surgery Surgical Margin Human Sensitivity and Specificity Prospective Studies kappa Statistic Frozen Sections Paraffin Embedding Turnaround Time Chondrosarcoma Osteosarcoma Sarcoma, Ewing's Giant Cell Tumors Predictive Value of Tests ab: Early and accurate detection of bone tumors and their staging are important since some of them are highly malignant. Intraoperative pathological consultation in bone tumors and tumor-like conditions is quite complex; however, it allows improvement in prognosis and limb salvage. Present study was conducted on 52 patients who underwent surgical procedure after clinical and radiological diagnosis of bone tumors/tumor-like conditions. Fresh unfixed tissue was quickly inspected grossly, followed by preparation of imprint smears and frozen section which were evaluated by two pathologists separately and compared subsequently with reports of paraffin-embedded sections. Clinical reasons for intraoperative consultation were to make diagnosis in 65.4% of cases and to determine resection margin status in 21.1%while in 13.5% of cases, it was for both indications. Diagnostic yield of imprint smears was 87.8% (13 malignant, 22 benign, and 1 tumor-like) and of frozen section was 90.2% (16 malignant, 19 benign, and 2 nonneoplastic) while paraffin sections could diagnose specific tumors in 95.1% (18 malignant, 18 benign, and 3 nonneoplastic). Although frozen section had better sensitivity (88.2%), it had less specificity (94.7%) as compared to imprint smears (76.5% and 100%, resp.). Imprint cytology and frozen section together provide a quick, safe, and reliable intraoperative provisional tissue diagnosis in skeletal tumors and tumor-like conditions. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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