Neurophysiological Indices of Atypical Auditory Processing and Multisensory Integration are Associated with Symptom Severity in Autism.
Atypical processing and integration of sensory inputs are hypothesized to play a role in unusual sensory reactions and social-cognitive deficits in autism spectrum disorder (ASD). Reports on the relationship between objective metrics of sensory processing and clinical symptoms, however, are surprisi...
| Publicado en: | Journal of Autism & Developmental Disorders Vol. 45; no. 1; pp. 230 - 245 |
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| Autores principales: | , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jan2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103871002&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103871002 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01623257 AUT jtl: Journal of Autism & Developmental Disorders issn: 01623257 maglogo: N pubinfo: dt: Jan2015 vid: 45 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 103871002 100301286 10.1007/s10803-014-2212-9 NLM25245785 103871002 ppf: 230 ppct: 15 formats: fmt: @attributes: type: P tig: atl: Neurophysiological Indices of Atypical Auditory Processing and Multisensory Integration are Associated with Symptom Severity in Autism. aug: au: Brandwein, Alice Foxe, John Butler, John Frey, Hans-Peter Bates, Juliana Shulman, Lisa Molholm, Sophie affil: Department of Pediatrics, The Sheryl and Daniel R. Tishman Cognitive Neurophysiology Laboratory, Children's Evaluation and Rehabilitation Center (CERC), Albert Einstein College of Medicine, 1225 Morris Park Avenue Bronx 10461 USA sug: subj: Autism Spectrum Disorder Symptoms Human Neurophysiology Sensation Child Adolescence Multiple Linear Regression Severity of Illness Auditory Perception Electrophysiology Experimental Studies Child: 6-12 years Adolescent: 13-18 years ab: Atypical processing and integration of sensory inputs are hypothesized to play a role in unusual sensory reactions and social-cognitive deficits in autism spectrum disorder (ASD). Reports on the relationship between objective metrics of sensory processing and clinical symptoms, however, are surprisingly sparse. Here we examined the relationship between neurophysiological assays of sensory processing and (1) autism severity and (2) sensory sensitivities, in individuals with ASD aged 6-17. Multiple linear regression indicated significant associations between neural markers of auditory processing and multisensory integration, and autism severity. No such relationships were apparent for clinical measures of visual/auditory sensitivities. These data support that aberrant early sensory processing contributes to autism symptoms, and reveal the potential of electrophysiology to objectively subtype autism. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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