Anterior cruciate ligament biomechanics during robotic and mechanical simulations of physiologic and clinical motion tasks: A systematic review and meta-analysis.

Investigators use in vitro joint simulations to invasively study the biomechanical behaviors of the anterior cruciate ligament. The aims of these simulations are to replicate physiologic conditions, but multiple mechanisms can be used to drive in vitro motions, which may influence biomechanical outc...

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Publicado en:Clinical Biomechanics Vol. 30; no. 1; pp. 1 - 14
Autores principales: Bates, Nathaniel A., Myer, Gregory D., Shearn, Jason T., Hewett, Timothy E.
Formato: research systematic review Journal Article
Publicado: Elsevier B.V. Jan2015
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Elsevier B.V.
      place: New York, New York
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        atl: Anterior cruciate ligament biomechanics during robotic and mechanical simulations of physiologic and clinical motion tasks: A systematic review and meta-analysis.
      aug:
        au:
          Bates, Nathaniel A.
          Myer, Gregory D.
          Shearn, Jason T.
          Hewett, Timothy E.
        affil: Department of Biomedical Engineering, University of Cincinnati, Cincinnati, OH, USA; The Sports Health and Performance Institute, OSU Sports Medicine, The Ohio State University, Columbus, OH, USA; Sports Medicine Biodynamics Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA
      sug:
        subj:
          Anterior Cruciate Ligament Physiology
          Biomechanics
          Motion
          Task Performance and Analysis
          Patient Simulation
          Robotics
          Human
          Systematic Review
          PubMed
          Medline
          SportDiscus
          Kinematics
          Kinetics
      ab: Investigators use in vitro joint simulations to invasively study the biomechanical behaviors of the anterior cruciate ligament. The aims of these simulations are to replicate physiologic conditions, but multiple mechanisms can be used to drive in vitro motions, which may influence biomechanical outcomes. The objective of this review was to examine, summarize, and compare biomechanical evidence related to anterior cruciate ligament function from in vitro simulations of knee motion. A systematic review was conducted (2004 to 2013) in Scopus, PubMed/Medline, and SPORTDiscus to identify peer-reviewed studies that reported kinematic and kinetic outcomes from in vitro simulations of physiologic or clinical tasks at the knee. Inclusion criteria for relevant studies were articles published in English that reported on whole-ligament anterior cruciate ligament mechanics during the in vitro simulation of physiologic or clinical motions on cadaveric knees that were unaltered outside of the anterior-cruciate-ligament-intact, -deficient, and -reconstructed conditions. A meta-analysis was performed to synthesize biomechanical differences between the anterior-cruciate-ligament-intact and reconstructed conditions. 77 studies met our inclusion/exclusion criteria and were reviewed. Combined joint rotations have the greatest impact on anterior cruciate ligament loads, but the magnitude by which individual kinematic degrees of freedom contribute to ligament loading during in vitro simulations is technique-dependent. Biomechanical data collected in prospective, longitudinal studies corresponds better with robotic-manipulator simulations than mechanical-impact simulations. Robotic simulation indicated that the ability to restore intact anterior cruciate ligament mechanics with anterior cruciate ligament reconstructions was dependent on loading condition and degree of freedom examined.
      pubtype: Academic Journal
      doctype:
        research
        systematic review
        Journal Article
      ougenre: Article
    language: English
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