Comparison of bone regeneration between octacalcium phosphate/collagen composite and β-tricalcium phosphate in canine calvarial defect.
Objective: The present study evaluated the efficacy of bone regeneration between synthetic octacalcium phosphate (OCP) granules combined with porcine atelocollagen (OCP/Col) and β-tricalcium phosphate (β-TCP). Study Design: A disk of OCP/Col (20 mm diameter, 2.5 mm thick) or commercially available s...
| Publicado en: | Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology Vol. 115; no. 1; pp. 9 - 18 |
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| Autores principales: | , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Elsevier B.V.
Jan2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103886578&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103886578 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 22124403 ETSG jtl: Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology issn: 22124403 maglogo: N pubinfo: dt: Jan2013 vid: 115 iid: 1 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 103886578 103886578 NLM22901651 2012701865 10.1016/j.oooo.2011.12.029 NLM22901651 103886578 ppf: 9 ppct: 9 formats: tig: atl: Comparison of bone regeneration between octacalcium phosphate/collagen composite and β-tricalcium phosphate in canine calvarial defect. aug: au: Tanuma, Yuji Matsui, Keiko Kawai, Tadashi Matsui, Aritsune Suzuki, Osamu Kamakura, Shinji Echigo, Seishi affil: Division of Oral Surgery, Department of Oral Medicine and Surgery, Graduate School of Dentistry, Tohoku University, Sendai, Japan. sug: subj: Bone Regeneration Drug Effects Collagen Pharmacodynamics Phosphates Pharmacodynamics Skull Drug Effects Animal Studies Biocompatible Materials Pharmacodynamics Bone Substitutes Pharmacodynamics Dogs Male Microradiography Skull Radiography X-Rays Male ab: Objective: The present study evaluated the efficacy of bone regeneration between synthetic octacalcium phosphate (OCP) granules combined with porcine atelocollagen (OCP/Col) and β-tricalcium phosphate (β-TCP). Study Design: A disk of OCP/Col (20 mm diameter, 2.5 mm thick) or commercially available sintered porous β-TCP was implanted into a critical-sized calvarial defect (20 mm diameter) of adult male canines (n = 10). The newly formed bone in the defect was analyzed radiographically, crystallographically, histologically, and histomorphometrically at 6 months after implantation. Results: Histomorphometry showed that there was significantly more newly formed bone in OCP/Col-treated defects than for β-TCP (P < .05). X-Ray diffraction patterns of implanted OCP/Col were similar to those of original bone and different from those of implanted β-TCP. Conclusions: These results suggest that OCP/Col implantation in canine critical-sized defect enhanced bone regeneration more than β-TCP, which is the most commonly used synthetic bone substitutes. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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